[4-(Propan-2-yl)-2-oxabicyclo[2.1.1]hexan-1-yl]methanol | 2241140-54-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [4-(Propan-2-yl)-2-oxabicyclo[2.1.1]hexan-1-yl]methanol
• 英文别名: (4-propan-2-yl-2-oxabicyclo[2.1.1]hexan-1-yl)methanol
• CAS: 2241140-54-3
• 化学式: C₉H₁₆O₂
• 分子量: 156.22
• InChiKey: LFARKNPHTWBYSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• 3-(5-AMINO-PYRAZIN-2-YL)-BENZENESULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PI3K-GAMMA KINASE INHIBITORS FOR TREATING E.G. CANCER
  申请人：Incyte Corporation

  公开号：US20200331903A1

  公开（公告）日：2020-10-22

  This application relates to compounds of Formula (I) or pharmaceutically acceptable salts thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.