4-chloro-5-[4-(3-hydroxypyrrolidin-1-yl)phenyl]-1-(4-methylsulfonylphenyl)imidazole | 372107-28-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-chloro-5-[4-(3-hydroxypyrrolidin-1-yl)phenyl]-1-(4-methylsulfonylphenyl)imidazole
• 英文别名: 1-[4-[5-Chloro-3-(4-methylsulfonylphenyl)imidazol-4-yl]phenyl]pyrrolidin-3-ol
• CAS: 372107-28-3
• 化学式: C₂₀H₂₀ClN₃O₃S
• 分子量: 417.916
• InChiKey: JSSVFTHMMRVHLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  83.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Novel heterocylic compounds with anti-inflamatory activity
  申请人：——

  公开号：US20030114456A1

  公开（公告）日：2003-06-19

  Novel heterocyclic compounds of formula I and the salts, solvates and prodrugs thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful as anti-inflammatories. 1

  式I的新型杂环化合物及其盐、溶剂合物和前药，其中各取代基的含义如描述中所披露。所述化合物可用作抗炎药物。
• NOVEL HETEROCYCLIC COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY
  申请人：J. URIACH & CIA. S.A.

  公开号：EP1281709A1

  公开（公告）日：2003-02-05

  Novel heterocyclic compounds of formula I and the salts, solvates and prodrugs thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful as anti-inflammatories.

  式 I 的新型杂环化合物及其盐类、溶液剂和原药，其中各种取代基的含义如说明中所披露。所述化合物可用作消炎药。