1,2-dichloro-5,6-dicyanobenzoquinone | 98166-92-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,2-dichloro-5,6-dicyanobenzoquinone
• 英文别名: DDQ；3,4-Dichloro-5,6-dioxocyclohexa-1,3-diene-1,2-dicarbonitrile
• CAS: 98166-92-8
• 化学式: C₈Cl₂N₂O₂
• 分子量: 227.006
• InChiKey: FWPLBKSOWVESRH-UHFFFAOYSA-N

物化性质

• 沸点：
  161.8±40.0 °C(Predicted)
• 密度：
  1.70±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  81.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  五羰基铁 、 二氯甲烷 、 1,2-dichloro-5,6-dicyanobenzoquinone 以 二氯甲烷 为溶剂， 生成 Fe[1,2-dichloro-5,6-dicyanobenzoquinone]2*1.02(CH2Cl2)
  参考文献：
  名称：

  Iron Pentacarbonyl as a Precursor for Molecule-Based Magnets:  Formation of Fe[TCNE]₂ (T_c = 100 K) and Fe[TCNQ]₂ (T_c = 35 K) Magnets

  摘要：

  The reaction of tetracyanoethylene (TCNE) and 7,7,8,8-tetracyano-p-quinodimethane (TCNQ) with Fe(CO)(5) leads to formation of magnetically ordered materials of Fe[TCNE](2) (T-c = 100 K) and Fe[TCNQ](2) (T-c = 35 K) composition, respectively. In contrast, the reaction with 1,2-dichloro-5,6-dicyanobenzoquinone (DDQ) leads to a paramagnetic material.

  DOI：

  10.1021/ic011288b

文献信息

• Arylsulfonyl naphthalene derivatives and uses thereof
  申请人：Harris New Ralph

  公开号：US20070293526A1

  公开（公告）日：2007-12-20

  Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, q, Ar, R 1 , R 2 and R 7 are as defined herein. Also provided are methods for preparing, compositions comprising, and methods for using compounds of formula I.

  化合物的公式I： 或其药用可接受的盐， 其中m、q、Ar、R1、R2和R7如本文所定义。还提供了制备方法、包含化合物I的组合物以及使用化合物I的方法。
• AMORPHOUS PYRROLIDINE DERIVATIVE AS PPAR AGONIST AND PREPARATION METHOD THEREOF
  申请人：GUANGDONG RAYNOVENT BIOTECH CO., LTD.

  公开号：US20200339508A1

  公开（公告）日：2020-10-29

  The present invention relates to an amorphous pyrrolidine derivative as a PPAR agonist and a preparation method thereof.

  这项发明涉及一种作为PPAR激动剂的非晶态吡咯烷衍生物及其制备方法。
• Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof
  申请人：MAILLIET Patrick

  公开号：US20080153837A1

  公开（公告）日：2008-06-26

  This invention relates to derivatives of 4-(benzimidazol-2-yl)fluorene and 4-(azabenzimidazol-2-yl)fluorene, to pharmaceutical compositions comprising such derivatives, and to methods of treatment of disorders related to Hsp90 protein activity, comprising administering such derivatives.

  这项发明涉及4-(苯并咪唑-2-基)芴和4-(氮杂苯并咪唑-2-基)芴的衍生物，涉及包含这些衍生物的药物组合物，以及涉及治疗与Hsp90蛋白活性相关的疾病的方法，包括给予这些衍生物。
• Glycosylated Carboranylporphyrins and Uses Thereof
  申请人：Miura Michiko

  公开号：US20080279781A1

  公开（公告）日：2008-11-13

  The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity glycosylated carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, and head and neck. The invention is also directed to using these glycosylated carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.

  本发明涉及低毒性硼化合物及其在肿瘤治疗、可视化和诊断中的使用方法。更具体地说，本发明涉及低毒性糖基化的含有5,10,15,20-四苯基卟啉的碳硼烷化合物及其在硼中子俘获治疗（BNCT）和光动力疗法（PDT）中的使用方法，特别用于治疗脑部、头颈部肿瘤。该发明还涉及使用这些糖基化的碳硼烷化合物在肿瘤成像和/或诊断方法中的应用，如MRI、SPECT或PET。
• NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90
  申请人：THOMPSON Fabienne

  公开号：US20100130503A1

  公开（公告）日：2010-05-27

  The present invention relates to compounds of formula (I): wherein R1, R 2 , R 2 ′, L, Het, p and p′ are as defined herein, compositions containing them, and their use as medicinal products.

  本发明涉及以下化合物的公式（I）：其中R1、R2、R2′、L、Het、p和p′如本文所定义，以及含有它们的组合物，并将它们用作药品。