4-fluoro-3',5'-dihydroxybenzophenone | 148253-51-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-fluoro-3',5'-dihydroxybenzophenone
• 英文别名: (3,5-Dihydroxyphenyl)(4-fluorophenyl)methanone；(3,5-dihydroxyphenyl)-(4-fluorophenyl)methanone
• CAS: 148253-51-4
• 化学式: C₁₃H₉FO₃
• 分子量: 232.211
• InChiKey: RWNPIRQOACQZIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-fluoro-3',5'-dihydroxybenzophenone 在 三氟甲磺酸三甲基硅酯 、 sodium carbonate 、 对甲苯磺酸 、 三氟乙酸 作用下， 以 乙醚 、 二甲基亚砜 、 丙酮 为溶剂， 反应 33.0h， 生成 {3,5-Bis-[4-(3,5-dimethoxy-benzoyl)-phenoxy]-phenyl}-(4-fluoro-phenyl)-methanone
  参考文献：
  名称：

  A convergent route to poly(phenyl ketone ether) dendrons

  摘要：

  A series of poly(phenyl ketone) dendrons have been constructed using a convergent strategy. An aryl fluoro-substituent is deactivated towards nucleophilic substitution by protection of a para-ketone as an acetal. This allows coupling to an activated aryl fluoride. Subsequent deprotection of the acetyl group then activates the first fluoro-substituent and allows the next generation of the dendron to be added. The synthesis of higher generations is complicated by a scrambling reaction, which lowers the yields. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.08.012
• 作为产物：
  描述：

  (4-氟-苯基)-(3,5-二甲氧基-苯基)-甲酮 在 三溴化硼 作用下， 生成 4-fluoro-3',5'-dihydroxybenzophenone
  参考文献：
  名称：

  A convergent route to poly(phenyl ketone ether) dendrons

  摘要：

  A series of poly(phenyl ketone) dendrons have been constructed using a convergent strategy. An aryl fluoro-substituent is deactivated towards nucleophilic substitution by protection of a para-ketone as an acetal. This allows coupling to an activated aryl fluoride. Subsequent deprotection of the acetyl group then activates the first fluoro-substituent and allows the next generation of the dendron to be added. The synthesis of higher generations is complicated by a scrambling reaction, which lowers the yields. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.08.012

文献信息

• [EN] AROMATIC HYPER BRANCHED POLYARYLETHERKETONE-BASED MEMBRANES FOR HIGH TEMPERATURE GAS SEPARATION<br/>[FR] MEMBRANES À BASE DE POLYARYLÉTHERCÉTONES HYPER-RAMIFIÉES AROMATIQUES POUR SÉPARATION DE GAZ À HAUTE TEMPÉRATURE
  申请人：UNIV NORTH CAROLINA CHAPEL HILL

  公开号：WO2020163777A1

  公开（公告）日：2020-08-13

  The invention generally relates to hyperbranched polymers and hyperbranched polymer networks and methods of making and using same. Specifically, the disclosed hyperbranched polymer networks can be incorporated into membranes, which can be useful in, for example, high temperature gas separation. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.