[3,6-dimethyl-2-(2,4,6-trimethoxy-phenoxy)-pyridin-4-yl]-(1-methoxymethyl-propyl)-amine | 351379-34-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [3,6-dimethyl-2-(2,4,6-trimethoxy-phenoxy)-pyridin-4-yl]-(1-methoxymethyl-propyl)-amine
• 英文别名: N-(1-methoxybutan-2-yl)-3,6-dimethyl-2-(2,4,6-trimethoxyphenoxy)pyridin-4-amine
• CAS: 351379-34-5
• 化学式: C₂₁H₃₀N₂O₅
• 分子量: 390.48
• InChiKey: SZAGUIKFWRIPHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  28
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  71.1
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Alpha- haloenamine reagents
  申请人：Pharmacia Corporation

  公开号：US20030080320A1

  公开（公告）日：2003-05-01

  The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.

  本发明描述了固定化的卤胺试剂、固定化的三级酰胺、其制备方法以及使用方法。
• Aromatic and heteroaromatic acid halides for synthesizing polyamides
  申请人：Pharmacia Corporation

  公开号：US20030105279A1

  公开（公告）日：2003-06-05

  The present invention is directed to protected amino acid halide monomers and oligomers, and to their use in the efficient sythesis of polyamides. The present invention is further directed to the use of &agr;-haloenamine reagents, which may optionally be immobilized, for the preparation of the amino acid halides.

  本发明涉及受保护的氨基酸卤代单体和寡聚体，以及它们在高效合成聚酰胺中的应用。本发明进一步涉及使用α-卤代胺试剂（可选择性固定）来制备氨基酸卤化物。
• Corticotropin releasing factor antagonists
  申请人：——

  公开号：US20020016328A1

  公开（公告）日：2002-02-07

  Corticotropin-releasing factor (CRF) antagonists having the formulae 1 wherein the dashed lines, A, B, Y, Z, G, R 3 , R 4 , R 5 , R 6 , R 16 and R 17 are as defined in the application, and processes for preparing them. These compounds and their pharmaceutically acceptable salts are useful in the treatment disorders including CNS and stress-related disorders.

  具有以下公式的促肾上腺皮质激素释放因子（CRF）拮抗剂，其中虚线、A、B、Y、Z、G、R3、R4、R5、R6、R16和R17如申请中所定义，并且制备它们的过程。这些化合物及其药用盐可用于治疗包括中枢神经系统和与压力相关的疾病。
• Alpha-haloenamine reagents
  申请人：Pharmacia Corporation

  公开号：US20040092770A1

  公开（公告）日：2004-05-13

  The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.

  本发明描述了固定化卤代烯胺试剂、固定化三级酰胺、它们的制备方法和使用方法。
• (ALPHA)-HALOENAMINE REAGENTS
  申请人：Pharmacia Corporation

  公开号：EP1421056A1

  公开（公告）日：2004-05-26