1-Ethoxyethyl-3-lithiopropylether | 88842-15-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Ethoxyethyl-3-lithiopropylether
• 英文别名: 3-[2-(ethoxy)-1-ethoxy]-1-propyllithium
• CAS: 88842-15-3
• 化学式: C₇H₁₅LiO₂
• 分子量: 138.136
• InChiKey: TZAJXUJFGQCTOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.02
• 重原子数：
  10.0
• 可旋转键数：
  7.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  1-Ethoxyethyl-3-lithiopropylether 生成
  参考文献：
  名称：

  分子内亲核攻击硅诱导的α-卤代硅烷重排

  摘要：

  有机基团从硅向碳的迁移通过硅的醇盐的分子内攻击而促进。

  DOI：

  10.1016/s0040-4039(00)61765-3

文献信息

• Generation of anionic intermediates by intramolecular nucleophilic attack at silicon
  作者：Paul F. Hudrlik、Yousef M. Abdallah、Anne M. Hudrlik

  DOI：10.1016/s0040-4039(00)61766-5

  日期：1992.11

  Benzyl and allyl anion equivalents can be generated from benzyl- and allylsilanes by intramolecular alkoxide attack.

  苄基和烯丙基阴离子可通过分子内醇盐的攻击从苄基和烯丙基硅烷中生成。
• Hetero-telechelic polymers and processes for making same
  申请人：——

  公开号：US20030013827A1

  公开（公告）日：2003-01-16

  Hetero-telechelic polymers having the formula: FG—(Q) d —Z—J—[A(R 1 R 2 R 3 )] x (1) wherein FG is a protected or non-protected functional group; Q is a saturated or unsaturated hydrocarbyl group derived by incorporation of a compound selected from the group consisting of conjugated diene hydrocarbons, alkenylsubstituted aromatic hydrocarbons, and mixtures thereof; d is an integer from 10 to 200; Z is a branched or straight chain hydrocarbon group which contains 3-25 carbon atoms, optionally containing aryl or substituted aryl groups; J is oxygen, sulfur, or nitrogen; [A(R 1 R 2 R 3 )] x is a protecting group, wherein A is an element selected from Group IVa of the Periodic Table of Elements; R 1 , R 2 , and R 3 are each independently selected from the group consisting of hydrogen, alkyl, substituted alkyl groups containing lower alkyl, lower alkylthio, and lower dialkylamino groups, aryl or substituted aryl groups containing lower alkyl, lower alkylthio, and lower dialkylamino groups, and cycloalkyl and substituted cycloalkyl containing 5 to 12 carbon atoms; and x is dependent on the valence of J and varies from one when J is oxygen or sulfur to two when J is nitrogen, with the proviso J and FG are not the same, and processes for making the same.

  具有以下化学式的杂交链烯聚合物 FG-(Q) d -Z-J-[A（R 1 R 2 R 3 )&rsqb； x (1) 其中，FG 是受保护或不受保护的官能团；Q 是饱和或不饱和的烃基，通过加入选自共轭二烯烃、烯基取代的芳香烃及其混合物的化合物而得到；d 是 10 到 200 之间的整数；Z 是含有 3-25 个碳原子的支链或直链烃基，可选择含有芳基或取代的芳基；J 是氧、硫或氮；[A(R 1) 1 R 2 R 3 )&rsqb； x 是保护基团，其中 A 是选自元素周期表第 IVa 族的元素；R 1 , R 2 和 R 3 各自独立地选自氢、烷基、含有低级烷基、低级烷硫基和低级二烷基氨基的取代烷基、含有低级烷基、低级烷硫基和低级二烷基氨基的芳基或取代芳基、以及含有 5 至 12 个碳原子的环烷基和取代环烷基组成的组；且 x 与 J 的价数有关，从 J 为氧或硫时的 1 到 J 为氮时的 2 不等，但 J 和 FG 不相同，以及制造相同物质的工艺。
• Processes for improving stability of living polymer chain ends
  申请人：FMC Corporation

  公开号：US20030114592A1

  公开（公告）日：2003-06-19

  Processes for improving the thermal stability of living polymer anions are provided. The invention further improves the efficiency of subsequent functionalization and linking reactions of such living polymer anions.

  本发明提供了提高活聚合物阴离子热稳定性的工艺。本发明进一步提高了此类活聚合物阴离子后续官能化和连接反应的效率。
• Functionalized alkyllithium formulations with improved thermal stability and processes for making the same
  申请人：FMC Corporation

  公开号：US20030114611A1

  公开（公告）日：2003-06-19

  Formulations of functionalized alkyllithium species having improved thermal stability are provided. The compositions include one or more functionalized alkyllithium compounds and one or more additives. The additive includes one or more organometallic compounds or precursors thereof capable of forming ate complexes with alkyllithiums.

  本发明提供了具有更好热稳定性的官能化烷基锂制剂。这些组合物包括一种或多种官能化烷锂化合物和一种或多种添加剂。添加剂包括一种或多种能与烷基锂形成ate络合物的有机金属化合物或其前体。
• Reactions of 3-hydroxyvinyl selenones with alkoxides. Oxetane formation and fragmentation reactions
  作者：Makoto Shimizu、Ryoichi Ando、Isao Kuwajima

  DOI：10.1021/jo00181a020

  日期：1984.4