(4R,5R)(-)-2-Phenyl-4,5-dicarbethoxy-1,3,2-dioxaphospholan | 80094-03-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (4R,5R)(-)-2-Phenyl-4,5-dicarbethoxy-1,3,2-dioxaphospholan
• 英文别名: (4R,5R)-4,5-dicarbethoxy-2-phenyl-1,3,2-dioxaphospholane；diethyl (4R,5R)-2-phenyl-1,3,2-dioxaphospholane-4,5-dicarboxylate
• CAS: 80094-03-7
• 化学式: C₁₄H₁₇O₆P
• 分子量: 312.259
• InChiKey: SJYWLESRXVSERM-VXGBXAGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.53
• 重原子数：
  21.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  71.06
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  三羰基(萘)铬 、 (4R,5R)(-)-2-Phenyl-4,5-dicarbethoxy-1,3,2-dioxaphospholan 以 四氢呋喃 、 正戊烷 为溶剂， 以2.8%的产率得到dicarbonyl{(4R,5R)-4,5-dicabethoxy-2-phenyl-1,3,2-dioxaphospolane}(η6-naphthalene)chromium(0)
  参考文献：
  名称：

  Efficient synthesis of substituted derivatives of (naphthalene)chromium(0) carbonyls

  摘要：

  Tricarbonyl(eta-6-1,4-epoxy-1,2,3,4-tetrahydronaphthalene) complex is a source of "protected" naphthalene for the indirect synthesis of Cr(eta-6-naphthalene)(CO)2L complexes, which can then be used in arene-exchange experiments. Experiments are reported for when L is a chiral 1,3,2-dioxaphospholane made by condensation of a chiral diol and PPhCl2. Direct photolysis reactions of these ligands with Cr(eta-6-naphthalene)(CO)3 gives the substituted complexes in very poor yield (< 3%). In contrast, photolysis reactions with the 1,4-epoxy-1,2,3,4-tetrahydronaphthalene complexes proceed in good (ca. 60-65%) yields, and subsequent dehydration by HBF4 and BF3 (ca. 50-65% yields) gives the substituted naphthalene complexes in an overall yield of 30-40% from the tricarbonyl. It is possible to exchange the naphthalene with monoarenes, though poor selectivity is observed in ligand-exchange experiments of the chiral naphthalene complexes with prochiral arenes.

  DOI：

  10.1021/om00047a069
• 作为产物：
  描述：

  L-(+)-酒石酸二乙酯 、 苯基二氯化磷 在 吡啶 作用下， 以 乙醚 为溶剂， 反应 8.0h， 以78%的产率得到(4R,5R)(-)-2-Phenyl-4,5-dicarbethoxy-1,3,2-dioxaphospholan
  参考文献：
  名称：

  Richter, Wolf Jurgen, Phosphorus and Sulfur and the Related Elements, 1981, vol. 10, p. 395 - 400

  摘要：

  DOI：

文献信息

• RICHTER, W. J., PHOSPH. AND SULFUR, 1981, 10, N 3, 395-400
  作者：RICHTER, W. J.

  DOI：——

  日期：——