6-cyclohexyl-2,2-dimethylhexan-3-one | 1011803-79-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-cyclohexyl-2,2-dimethylhexan-3-one
• CAS: 1011803-79-4
• 化学式: C₁₄H₂₆O
• 分子量: 210.36
• InChiKey: QGERFMFRMSQUFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Fused heterocycle derivative
  申请人：Sawada Takashi

  公开号：US20090239853A1

  公开（公告）日：2009-09-24

  A fused heterocycle derivative represented by the general formula (I): (wherein R 1 represents optionally substituted lower alkyl, or the like; R 2 represents an optionally substituted aliphatic heterocyclic group, or the like; R 3 represents —C(=Z)NR 5 R 6 (wherein R 5 and R 6 represent optionally substituted lower alkyl, or the like, and Z represents an oxygen atom or the like), or the like; n represents an integer of 1 to 3; and W represents C—R 5 (wherein R 5 represents a hydrogen atom or the like)) or a pharmaceutically acceptable salt thereof, and the like are provided.

  提供一种由通式（I）表示的融合杂环衍生物：（其中R1代表可选取代的低碳基等；R2代表可选取代的脂肪族杂环基等；R3代表—C（=Z）NR5R6（其中R5和R6代表可选取代的低碳基等，Z代表氧原子等）等；n代表1到3的整数；W代表C—R5（其中R5代表氢原子等）或类似物的药物可接受的盐等。
• COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR
  申请人：Bartolozzi Alessandra

  公开号：US20120316173A1

  公开（公告）日：2012-12-13

  Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  公式（I）的化合物已被揭示。本发明的化合物与CB2受体结合，并且是激动剂、拮抗剂或反向激动剂，可用于治疗炎症。那些是激动剂的化合物还可用于治疗疼痛。
• FUSED HETEROCYCLIC DERIVATIVE
  申请人：Kyowa Hakko Kirin Co., Ltd.

  公开号：EP2070927A1

  公开（公告）日：2009-06-17

  A fused heterocycle derivative represented by the general formula (I): (wherein R1 represents optionally substituted lower alkyl, or the like; R2 represents an optionally substituted aliphatic heterocyclic group, or the like; R3 represents -C(=Z)NR5R6 (wherein R5 and R6 represent optionally substituted lower alkyl, or the like, and Z represents an oxygen atom or the like), or the like; n represents an integer of 1 to 3; and W represents C-R5 (wherein R5 represents a hydrogen atom or the like)) or a pharmaceutically acceptable salt thereof, and the like are provided.

  通式 (I) 所代表的融合杂环衍生物： (其中 R1 代表任选取代的低级烷基或类似物；R2 代表任选取代的脂肪杂环基团或类似物；R3 代表-C(=Z)NR5R6（其中 R5 和 R6 代表任选取代的低级烷基或类似物，Z 代表氧原子或类似物）或类似物；n 代表 1 至 3 的整数；W 代表 C-R5（其中 R5 代表氢原子或类似物））或其药学上可接受的盐等。
• US8236841B2
  申请人：——

  公开号：US8236841B2

  公开（公告）日：2012-08-07
• US9315454B2
  申请人：——

  公开号：US9315454B2

  公开（公告）日：2016-04-19