| 1215220-10-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• CAS: 1215220-10-2
• 化学式: C₂₀H₁₉N₃O
• 分子量: 317.39
• InChiKey: FEFVHMQZAIQUDO-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  C₂₀H₂₀FN₃O 以 二甲基亚砜 为溶剂， 反应 1.0h， 生成
  参考文献：
  名称：

  Preparation of 2,4,5-trisubstituted pyrazolo[4,3-c]quinolin-3-ones

  摘要：

  The preparation of pyrazolo[4,3-c]quinolinones is reported starting from 2-substituted-5-(2-fluorophenyl)-3-oxo-2,4-dihydro-3H-pyrazol-3-ones. A one-pot protocol was developed, in which condensation with an orthoamide, followed by substitution with a primary amine and subsequent S(N)Ar-cyclization, to provide rapid access to 4- and 5-substituted pyrazolo[4,3-c]quinolinones. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.12.054