Chemically bonded cationic β-cyclodextrin derivatives as chiral stationary phases for enantioseparation applications
摘要:
Vinylene-functionalized cationic beta-cyclodextrins are co-polymerized with vinylized silica in the presence of AIBN and conjugated monomers. The chemically immobilized cationic beta-cyclodextrins were thereafter applied as chiral stationary phases in packed column supercritical fluid chromatography and demonstrated good and reproducible enantioseparations of racemic pharmaceutical compounds. (C) 2012 Elsevier Ltd. All rights reserved.
Chemically bonded cationic β-cyclodextrin derivatives as chiral stationary phases for enantioseparation applications
摘要:
Vinylene-functionalized cationic beta-cyclodextrins are co-polymerized with vinylized silica in the presence of AIBN and conjugated monomers. The chemically immobilized cationic beta-cyclodextrins were thereafter applied as chiral stationary phases in packed column supercritical fluid chromatography and demonstrated good and reproducible enantioseparations of racemic pharmaceutical compounds. (C) 2012 Elsevier Ltd. All rights reserved.