bis(tert.-butylamino)-(indol-1-yl)phenylsilan | 180139-21-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: bis(tert.-butylamino)-(indol-1-yl)phenylsilan
• 英文别名: N-[(tert-butylamino)-indol-1-yl-phenylsilyl]-2-methylpropan-2-amine
• CAS: 180139-21-3
• 化学式: C₂₂H₃₁N₃Si
• 分子量: 365.594
• InChiKey: MFEKBBHALVCPBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.11
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  29
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  bis(tert.-butylamino)-(indol-1-yl)phenylsilan 在 正丁基锂 、 silicon tetrafluoride 作用下， 生成 1.3-di-tert.-butyl-2.2-difluor-4-(indol-1-yl)-4-phenylcyclodisilazan
  参考文献：
  名称：

  INDOL-1-YL-UND-(PYRROL-1-YL)-CYCLODI-UND-TRISILAZANE-SYNTHESE UND RINGKONTRAKTION

  摘要：

  Dichloro(indol-1-yl)silanes react with lithium-tert.-butylamide to mono- and bis(amino)-(indol-1-yl)silanes 1-3. In addition to this dichlorobis(pyrrol-1-yl)silane and lithium-tert.-butylamide give the bis(amino)-bis(pyrrol-1-yl)silane 4, however, with tert.-butylamine the mono(amino)-chlorobis(pyrrol-1-yl)silane 5 is formed. 3 and 5 are two more examples for the rare NH-functional chlorosilanes. Depending on the stoichiometry the methylamino(pyrrol-1-yl)silanes 6 and 7 are formed in the reaction of dichlorobis(pyrrolyl-1-yl)silane and methylamine. 7 is formed with displacement of the pyrrolyl-substituent by the more basic methylamino-group. 1 and 2 can be dilithiated and added to difluorosilanes leading to the cyclodisilazanes 8-10. 1.3.5-Tris(fluorodimethylsilyl)hexamethylcyclotrisilazane is an educt for pyrrol-1-yl- and (indol-1-yl)silylhexamethylcyclotrisilazanes 11-14. It reacts with one equivalent of lithiumpyrrolide or -indolide to 11 and 12 or with two or three equivalents of lithiumpyrrolide to 13 and 14. The 1.3-bis((N-(indol-1-yl)dimethylsilyl)aminodimethylsilyl)-2.4-bis(dimethyl)cyclodisilazane 15 is formed in the reaction of 1.5-bis(fluorodimethylsilyl)octamethylcyclotetrasilazane with lithiumindolide which catalyzes the ringcontraction. The crystal structure of 14 is reported.

  DOI：

  10.1080/10426509608046359
• 作为产物：
  描述：

  叔丁胺 、 dichloro-indol-1-yl-phenylsilane 在 正丁基锂 作用下， 生成 tert.-butylaminochlor(indol-1-yl)phenylsilan 、 bis(tert.-butylamino)-(indol-1-yl)phenylsilan
  参考文献：
  名称：

  INDOL-1-YL-UND-(PYRROL-1-YL)-CYCLODI-UND-TRISILAZANE-SYNTHESE UND RINGKONTRAKTION

  摘要：

  Dichloro(indol-1-yl)silanes react with lithium-tert.-butylamide to mono- and bis(amino)-(indol-1-yl)silanes 1-3. In addition to this dichlorobis(pyrrol-1-yl)silane and lithium-tert.-butylamide give the bis(amino)-bis(pyrrol-1-yl)silane 4, however, with tert.-butylamine the mono(amino)-chlorobis(pyrrol-1-yl)silane 5 is formed. 3 and 5 are two more examples for the rare NH-functional chlorosilanes. Depending on the stoichiometry the methylamino(pyrrol-1-yl)silanes 6 and 7 are formed in the reaction of dichlorobis(pyrrolyl-1-yl)silane and methylamine. 7 is formed with displacement of the pyrrolyl-substituent by the more basic methylamino-group. 1 and 2 can be dilithiated and added to difluorosilanes leading to the cyclodisilazanes 8-10. 1.3.5-Tris(fluorodimethylsilyl)hexamethylcyclotrisilazane is an educt for pyrrol-1-yl- and (indol-1-yl)silylhexamethylcyclotrisilazanes 11-14. It reacts with one equivalent of lithiumpyrrolide or -indolide to 11 and 12 or with two or three equivalents of lithiumpyrrolide to 13 and 14. The 1.3-bis((N-(indol-1-yl)dimethylsilyl)aminodimethylsilyl)-2.4-bis(dimethyl)cyclodisilazane 15 is formed in the reaction of 1.5-bis(fluorodimethylsilyl)octamethylcyclotetrasilazane with lithiumindolide which catalyzes the ringcontraction. The crystal structure of 14 is reported.

  DOI：

  10.1080/10426509608046359