4-{[5,7-二(三氟甲基)-1,8-萘啶-2-基]氧基}-N-(3-吡啶基甲基)苯磺酰胺 | 338412-13-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-{[5,7-二(三氟甲基)-1,8-萘啶-2-基]氧基}-N-(3-吡啶基甲基)苯磺酰胺
• 中文别名: N~6~-乙酰基-N~6~-羟基-L-赖氨酸
• 英文名称: 4-{[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]oxy}-N-(3-pyridinylmethyl)benzenesulfonamide
• 英文别名: 4-[[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]oxy]-N-(pyridin-3-ylmethyl)benzenesulfonamide
• CAS: 338412-13-8
• 化学式: C₂₂H₁₄F₆N₄O₃S
• 分子量: 528.4
• InChiKey: DMUJKGCAZMKIEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  36
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  102
• 氢给体数：
  1
• 氢受体数：
  13

文献信息

• COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS
  申请人：Trent John O.

  公开号：US20130059852A1

  公开（公告）日：2013-03-07

  Some embodiments of this invention include methods for treating disease and methods for administering a compound of Formula (I). In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of Formula (I). Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I).
• US8785490B2
  申请人：——

  公开号：US8785490B2

  公开（公告）日：2014-07-22
• US9145398B2
  申请人：——

  公开号：US9145398B2

  公开（公告）日：2015-09-29
• [EN] COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS<br/>[FR] COMPOSÉS POUR LE TRAITEMENT D'UNE MALADIE, POUR L'ADMINISTRATION, ET POUR DES COMPOSITIONS PHARMACEUTIQUES
  申请人：UNIV LOUISVILLE RES FOUND

  公开号：WO2011127333A2

  公开（公告）日：2011-10-13

  Some embodiments of this invention include methods for treating disease and methods for administering a compound of Formula (I). In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of Formula (I). Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I).