2,3-O-isopropylidene-1-O-decyl-5,6-dideoxy-5-amino-β-L-5-gulofuranoside | 1102075-31-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3-O-isopropylidene-1-O-decyl-5,6-dideoxy-5-amino-β-L-5-gulofuranoside
• 英文别名: 2,3-O-isopropylidene-1-O-decyl-5,6-dideoxy-5-amino-α,D-5-epimannofuranoside；(1S)-1-[(3aS,4S,6R,6aS)-4-decoxy-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]ethanamine
• CAS: 1102075-31-9
• 化学式: C₁₉H₃₇NO₄
• 分子量: 343.507
• InChiKey: UMROKJZQLZOWDY-ADHGMGHFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  24
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  62.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS
  申请人：RANBAXY LABORATORIES, LTD.

  公开号：EP1144425A1

  公开（公告）日：2001-10-17
• [EN] DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS<br/>[FR] DERIVES DE MONOSACCHARIDES EN TANT QU'INHIBITEURS DE L'ADHESION CELLULAIRE
  申请人：RANBAXY LAB LTD

  公开号：WO2000042053A1

  公开（公告）日：2000-07-20

  The present application relates to a group of novel substituted pentose and hexose monosaccharide derivatives, not previously disclosed, which exhibit potent anti-cell adhesion and anti-inflammatory activities. Methods of preparation, pharmaceutical compositions containing the compounds and methods of treatment, suppression and prevention of cell adhesion mediated chronic inflammatory disorders are also described.