D-Fuc2Br(b1-3)a-Qui1F2I4Ac | 548463-44-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: D-Fuc2Br(b1-3)a-Qui1F2I4Ac
• 英文别名: [(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3-bromo-4,5-dihydroxy-6-methyloxan-2-yl]oxy-6-fluoro-5-iodo-2-methyloxan-3-yl] acetate
• CAS: 548463-44-1
• 化学式: C₁₄H₂₁BrFIO₇
• 分子量: 527.123
• InChiKey: NHUJOXPXJKJOSD-DRTVZLRTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  原乙酸三甲酯 、 D-Fuc2Br(b1-3)a-Qui1F2I4Ac 以 水 为溶剂， 反应 0.5h， 以91%的产率得到C₁₆H₂₃BrFIO₈
  参考文献：
  名称：

  Recent advances in the synthesis of 2-deoxy-glycosides

  摘要：

  Glycosides of 2-deoxy-sugars, monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom, occur widely in natural products and therefore have been the subject of intense synthetic activity. The report summarizes recent advances in this area, with a particular focus on work published since an earlier review on the topic, in 2000 (Marzabadi, C. H.: Franck, R. W. Tetrahedron 2000, 56, 8385-8417). (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.07.013
• 作为产物：
  描述：

  在 potassium carbonate 作用下， 以 甲醇 为溶剂， 以93%的产率得到D-Fuc2Br(b1-3)a-Qui1F2I4Ac
  参考文献：
  名称：

  Recent advances in the synthesis of 2-deoxy-glycosides

  摘要：

  Glycosides of 2-deoxy-sugars, monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom, occur widely in natural products and therefore have been the subject of intense synthetic activity. The report summarizes recent advances in this area, with a particular focus on work published since an earlier review on the topic, in 2000 (Marzabadi, C. H.: Franck, R. W. Tetrahedron 2000, 56, 8385-8417). (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.07.013