N-benzyl-3-[(E)-hept-2'-enyl]-3-methyloxindole | 122128-47-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: N-benzyl-3-[(E)-hept-2'-enyl]-3-methyloxindole
• 英文别名: 1-benzyl-3-[(E)-hept-2-enyl]-3-methylindol-2-one
• CAS: 122128-47-6
• 化学式: C₂₃H₂₇NO
• 分子量: 333.473
• InChiKey: RGWUSOHMVGIPNY-WUXMJOGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-[(E)-1-hexenyl]-1,3,2-benzodioxaborole 、 N-苄基-N-(2-碘苯基)甲基丙烯酰胺 在 palladium diacetate sodium ethanolate 、 三苯基膦 作用下， 以 乙醇 、 苯 为溶剂， 反应 5.0h， 以32.5%的产率得到N-benzyl-3-[(E)-hept-2'-enyl]-3-methyloxindole
  参考文献：
  名称：

  Palladium catalysed tandem cyclisation-anion capture processes. Part 3. Organoboron anion transfer agents

  摘要：

  The cyclisation-anion capture protocol has been applied to a wide range of starter and terminating species to effect regio-and stereo-specific mono-and bis-cyclisation processes in which a variety of organoboronderivatives function as anion transfer reagents. Direct capture (no cyclisation) is rarely a problem and it can usually be suppressed by modification of the reaction conditions. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00754-0

文献信息

• Regiospecific palladium catalysed tandem cyclisation-anion capture processes. Stereospecific group transfer from organozinc and organoboron reagents
  作者：Barry Burns、Ronald Grigg、Visuvanathar Sridharan、Paul Stevenson、Sukanthini Sukirthalingam、Tanachat Worakun

  DOI：10.1016/s0040-4039(01)80380-4

  日期：1989.1
• BURNS, BARRY;GRIGG, RONALD;SRIDHARAN, VISUVANATHAR;STEVENSON, PAUL;SUKIRT+, TETRAHEDRON LETT., 30,(1989) N, C. 1135-1138
  作者：BURNS, BARRY、GRIGG, RONALD、SRIDHARAN, VISUVANATHAR、STEVENSON, PAUL、SUKIRT+

  DOI：——

  日期：——
• Palladium catalysed tandem cyclisation-anion capture processes. Part 3. Organoboron anion transfer agents
  作者：Ronald Grigg、JoséM. Sansano、Vijayaratnam Santhakumar、Visuvanathar Sridharan、Ravishanker Thangavelanthum、Mark Thornton-Pett、David Wilson

  DOI：10.1016/s0040-4020(97)00754-0

  日期：1997.8

  The cyclisation-anion capture protocol has been applied to a wide range of starter and terminating species to effect regio-and stereo-specific mono-and bis-cyclisation processes in which a variety of organoboronderivatives function as anion transfer reagents. Direct capture (no cyclisation) is rarely a problem and it can usually be suppressed by modification of the reaction conditions. (C) 1997 Elsevier Science Ltd.