Ethyl-3-pentadien-1,2-ol-4 | 17615-21-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Ethyl-3-pentadien-1,2-ol-4
• 英文别名: 3-Aethyl-pentadien-(1.2)-ol-(4)；3-ethyl-penta-3,4-dien-2-ol
• CAS: 17615-21-3
• 化学式: C₇H₁₂O
• 分子量: 112.172
• InChiKey: PHYJIZJZWNGLNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Orthoester compositions for affinity purification of oligonucleotides
  申请人：Agilent Technologies, Inc.

  公开号：US11299483B2

  公开（公告）日：2022-04-12

  Compounds and methods for purifying oligonucleotides such as RNA and DNA. A target oligonucleotide is reacted with an orthoester linker comprising an affinity tag to form an orthoester oligonucleotide-orthoester linker conjugate which is subjected to a purification technique to separate the target oligonucleotide from impurities such as truncated oligonucleotides. The orthoester linker can be then removed under mild conditions to generate the target oligonucleotide in high purity.

  用于纯化 RNA 和 DNA 等寡核苷酸的化合物和方法。目标寡核苷酸与包含亲和性标签的正交酯连接体反应，形成正交酯寡核苷酸-正交酯连接体共轭物，该共轭物通过纯化技术从截短寡核苷酸等杂质中分离出目标寡核苷酸。然后在温和的条件下去除正交酯连接体，生成高纯度的目标寡核苷酸。
• ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES
  申请人：Agilent Technologies, Inc.

  公开号：EP3668883A1

  公开（公告）日：2020-06-24
• [EN] ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES<br/>[FR] COMPOSITIONS D'ORTHOESTER DESTINÉES À LA PURIFICATION PAR AFFINITÉ D'OLIGONUCLÉOTIDES
  申请人：AGILENT TECHNOLOGIES INC

  公开号：WO2019036029A1

  公开（公告）日：2019-02-21

  Compounds and methods for purifying oligonucleotides such as RNA and DNA. A target oligonucleotide is reacted with an orthoester linker comprising an affinity tag to form an orthoester oligonucleotide-orthoester linker conjugate which is subjected to a purification technique to separate the target oligonucleotide from impurities such as truncated oligonucleotides. The orthoester linker can be then removed under mild conditions to generate the target oligonucleotide in high purity.