2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-α-D-galactopyranose | 177565-66-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-α-D-galactopyranose
• 英文别名: beta-D-GalpNAc-(1->3)-alpha-D-GalpNAc；N-[(2R,3R,4R,5R,6R)-2-[(2S,3R,4R,5R,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
• CAS: 177565-66-1
• 化学式: C₁₆H₂₈N₂O₁₁
• 分子量: 424.405
• InChiKey: FJGXDMQHNYEUHI-RWUFDMEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  207
• 氢给体数：
  8
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  在 水 作用下， 以 aq. buffer 为溶剂， 生成 2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-α-D-galactopyranose
  参考文献：
  名称：

  [EN] ACHOLETIN BIOPOLYMERS AND METHODS FOR ENZYMATIC SYNTHESIS
  [FR] BIOPOLYMÈRES D'ACHOLÉTINE ET PROCÉDÉS DE SYNTHÈSE ENZYMATIQUE

  摘要：

  Provided herein are β-1,3-linked biopolymers (acholetin polysaccharides). Furthermore, provided herein are enzymatic methods and systems for producing β-1,3-linked oligosaccharides and polysaccharides using β-1,3-N-acetylglucosaminide phosphorylase (Acholetin phosphorylase (AchP)). The AchP was sourced from the genome of the cell wall-less Mollicute bacterium, Acholeplasma laidlawii and was found to synthesize β-1,3-linked N-acetylglucosamine (GlcNAc) or N-acetylgalactosamine (GalNAc) oligomers using the donor, α-N-acetylglucosamine 1-phosphate (GlcNAc1-P) or N-acetylgalactosamine 1-phosphate (GalNAc1-P).

  公开号：

  WO2022256920A1