| 198706-77-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 198706-77-3
• 化学式: C₂₄H₄₃N₃O₆Si₂
• 分子量: 525.793
• InChiKey: XARNNGIBSNUNBQ-CXFIUDIKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.42
• 重原子数：
  35.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  115.71
• 氢给体数：
  1.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  在 水 作用下， 生成
  参考文献：
  名称：

  Novel Analogues of the Anti-HIV-1 Agent TSAO-T Modified at the 3′-Spiro Moiety

  摘要：

  Novel TSAO-T analogues, in which the 3'-spiroaminooxatioledioxide moiety has been replaced by other 3'-spiro moieties bearing a NH group at the same position as the 4 ''-NH2 of TSAO-T have been prepared and evaluated for their inhibitory effect on HIV replication in cell culture. In contrast to the prototype compound TSAO-T, the novel TSAO derivatives were inactive at subtoxic concentrations.

  DOI：

  10.1080/07328319708006126
• 作为产物：
  描述：

  3-Methylthymidin 在 chromium(VI) oxide 、 碳酸氢钠 作用下， 以 吡啶 为溶剂， 生成
  参考文献：
  名称：

  Novel Analogues of the Anti-HIV-1 Agent TSAO-T Modified at the 3′-Spiro Moiety

  摘要：

  Novel TSAO-T analogues, in which the 3'-spiroaminooxatioledioxide moiety has been replaced by other 3'-spiro moieties bearing a NH group at the same position as the 4 ''-NH2 of TSAO-T have been prepared and evaluated for their inhibitory effect on HIV replication in cell culture. In contrast to the prototype compound TSAO-T, the novel TSAO derivatives were inactive at subtoxic concentrations.

  DOI：

  10.1080/07328319708006126