2-amino-2-deoxy-β-D-galactopyranosylhydrazine | 131158-05-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-amino-2-deoxy-β-D-galactopyranosylhydrazine
• 英文别名: (2R,3R,4R,5R,6R)-5-amino-6-hydrazinyl-2-(hydroxymethyl)oxane-3,4-diol
• CAS: 131158-05-9
• 化学式: C₆H₁₅N₃O₄
• 分子量: 193.203
• InChiKey: AAJGJSRYAIJXJR-VFUOTHLCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.78
• 重原子数：
  13.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  133.99
• 氢给体数：
  6.0
• 氢受体数：
  7.0

反应信息

• 作为产物：
  描述：

  2-氨基-2-脱氧-D-半乳糖盐酸盐 在 肼 作用下， 反应 30.0h， 生成 2-amino-2-deoxy-β-D-galactopyranosylhydrazine 、 1-deoxy-D-tagatose hydrazone 、 2-amino-2-deoxy-D-galactose hydrazone
  参考文献：
  名称：

  A comparison of the results of sequential hydrazinolysis-nitrosation and alkali-mediated cleavage-nitrosation of theO-linked oligosaccharides of gastric mucus glycoproteins

  摘要：

  Analysis of the oligosaccharides released from pig gastric mucus glycopolypeptides by hydrazinolysis showed that degradation had occurred. Nitrosation of the products followed by reduction gave a mixture that had a low content of 2,5-anhydro-D-talitol, which implied destruction of much of the terminal reducing 2-amino-2-deoxy-D-galactose. Under the conditions of hydrazinolysis, cellobiose was largely unchanged but laminaribiose gave a complex mixture that probably contained glucose hydrazone (13C-n.m.r. data). In order to avoid degradation, the hydrazinolysis-nitrosation sequence should be applied to the reduced oligosaccharides released on cleavage with alkali.

  DOI：

  10.1016/0008-6215(90)80138-s