1,3-dihydro-7-iodo-3-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoro-methyl)ethyl]phenylimino}-2-benzofuran-1-one | 476311-56-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异香豆素
• 英文名称: 1,3-dihydro-7-iodo-3-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoro-methyl)ethyl]phenylimino}-2-benzofuran-1-one
• 英文别名: 3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]imino-7-iodo-2-benzofuran-1-one
• CAS: 476311-56-5
• 化学式: C₁₈H₉F₇INO₂
• 分子量: 531.168
• InChiKey: KFNZRFZBXIGOSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  29
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  2-amino-2-methylpropane-1-sulfonamide acetate 、 1,3-dihydro-7-iodo-3-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoro-methyl)ethyl]phenylimino}-2-benzofuran-1-one 在 三乙胺 作用下， 以 乙腈 为溶剂， 反应 30.0h， 以9%的产率得到3-iodo-N¹-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-N²-(2-sulfamoyl-1,1-dimethylethyl)phthalamide
  参考文献：
  名称：

  EP1544193

  摘要：

  公开号：
• 作为产物：
  描述：

  2-甲基-4-七氟异丙基苯胺 、 4-碘异苯并呋喃-1,3-二酮 在 三氟乙酸酐 作用下， 以 甲苯 为溶剂， 以100%的产率得到1,3-dihydro-7-iodo-3-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoro-methyl)ethyl]phenylimino}-2-benzofuran-1-one
  参考文献：
  名称：

  Novel diamide insecticides: Sulfoximines, sulfonimidamides and other new sulfonimidoyl derivatives

  摘要：

  Novel insecticidal anthranilamides with elaborated sulfur-containing groups are described. The synthesis of compounds with functional groups such as sulfoximines and scarcely reported groups such as sulfonimidoyl hydrazides and hydroxylamides, their in vitro and in vivo biological activity as well as their physical properties are reported. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.03.106

文献信息

• Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof
  申请人：Yamaguchi Minoru

  公开号：US20060167315A1

  公开（公告）日：2006-07-27

  Sulfonamide derivatives represented by general formula (I) or salts thereof; insecticides for agricultural and horticultural use containing the same as the active ingredient; and usage thereof: [wherein A is optionally substituted (C 1 -C 6 )alkylene, (C 3 -C 6 )alkenylene or the like; R 1 is H, optionally substituted (C 1 -C 6 )alkyl, (C 3 -C 6 )alkenyl, (C 3 -C 6 )cycloalkyl or the like; R 2 , R 3 and R 4 are each H, (C 1 -C 6 )alkyl, (C 3 -C 6 )alkenyl or the like, or R 2 and A or R 2 and R 1 may form a 3- to 8-membered ring which may be interrupted by one to three atoms selected from among Of S and N; Q is C or N; X and Y are each halogen, CN, NO 2 , (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl or the like; m is 0 to 2; n is 0 to 3; and two adjacent Xs or Ys on the aromatic ring may be united to form a fused ring]. The compounds exhibit excellent insecticidal activity against insect pests resistant to existing pesticides even when applied in dosages lower than those of similar pesticides.

  通式（I）或其盐所代表的磺胺衍生物；农业和园艺用杀虫剂，其包含作为活性成分的磺胺衍生物；以及其用途：[其中A是可选取代的（C1-C6）烷基，（C3-C6）烯基或类似物；R1为H，可选取代的（C1-C6）烷基，（C3-C6）烯基，（C3-C6）环烷基或类似物；R2，R3和R4分别为H，（C1-C6）烷基，（C3-C6）烯基或类似物，或R2和A或R2和R1可以形成一个3-到8-成员的环，该环可以被选自O、S和N的1-3个原子所中断；Q为C或N；X和Y分别为卤素，CN，NO2，（C1-C6）烷基，（C2-C6）烯基或类似物；m为0到2；n为0到3；芳香环上的两个相邻的X或Y可以合并形成一个融合环]。这些化合物表现出优异的杀虫活性，对于已经对现有杀虫剂产生抗性的害虫来说，即使在比类似杀虫剂更低的剂量下应用，也能够有效地控制。