decahydro-naphthalene-2,3-diol | 57397-07-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: decahydro-naphthalene-2,3-diol
• 英文别名: 2.3-Dioxy-dekahydronaphthalin；Decahydro-naphthalin-2,3-diol；Dekalin-diol-(2.3)；2.3-Dioxy-dekalin；9β,10α-Decalin-2β,3β-diol；Decahydro-2,3-naphthalenediol；1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene-2,3-diol
• CAS: 57397-07-6
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: WTIPFYCAMXYLQJ-UHFFFAOYSA-N

物化性质

• 熔点：
  141 °C
• 沸点：
  314.3±10.0 °C(Predicted)
• 密度：
  1.117±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  硫酸 、 decahydro-naphthalene-2,3-diol 、 alkaline earth salt of/the/ methylsulfuric acid 生成 cyclohexane-1,2-diyldi-acetic acid
  参考文献：
  名称：

  Leroux, Annales de Chimie (Cachan, France), 1910, vol. <8> 21, p. 509,521

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 acid 作用下， 生成 decahydro-naphthalene-2,3-diol
  参考文献：
  名称：

  Leroux, Annales de Chimie (Cachan, France), 1910, vol. <8> 21, p. 509,521

  摘要：

  DOI：

文献信息

• Process for Preparing Optically Active Diphosphanes
  申请人：Jaekel Christoph

  公开号：US20080242893A1

  公开（公告）日：2008-10-02

  The present invention relates to a process for preparing optically active bisphosphinylalkanes from the correspondingly substituted, racemic 1,2-diols. The optically active bisphosphinylalkanes which can be obtained in this way are suitable as ligands for preparing chiral transition metal catalysts.

  本发明涉及一种从相应取代的外消旋1,2-二醇制备光学活性双膦烷的方法。通过这种方法可以获得的光学活性双膦烷适用作制备手性过渡金属催化剂的配体。
• LATENT CATALYST FOR EPOXY RESIN, EPOXY RESIN COMPOSITION, AND SEMICONDUCTOR DEVICE
  申请人：Horimoto Akihiro

  公开号：US20090023840A1

  公开（公告）日：2009-01-22

  The present invention provides a latent catalyst for epoxy resin, comprising: a cation moiety having an activity of accelerating curing reaction of epoxy resin; and a silicate anion moiety of suppressing the curing reaction-accelerating activity. Also disclosed are an epoxy resin composition comprising the latent catalyst and a semiconductor device using the epoxy resin composition.

  本发明提供了一种环氧树脂的潜在催化剂，包括：具有加速环氧树脂固化反应活性的阳离子基团；以及抑制固化反应加速活性的硅酸盐阴离子基团。还公开了一种包含潜在催化剂的环氧树脂组合物以及使用该环氧树脂组合物的半导体器件。
• Latent catalyst for epoxy resin, epoxy resin composition, and semiconductor device
  申请人：Horimoto Akihiro

  公开号：US20050075474A1

  公开（公告）日：2005-04-07

  The present invention provides a latent catalyst for epoxy resin, comprising: a cation moiety having an activity of accelerating curing reaction of epoxy resin; and a silicate anion moiety of suppressing the curing reaction-accelerating activity. Also disclosed are an epoxy resin composition comprising the latent catalyst and a semiconductor device using the epoxy resin composition.

  本发明提供了一种环氧树脂的潜在催化剂，包括：具有加速环氧树脂固化反应活性的阳离子基团；以及抑制固化反应加速活性的硅酸盐阴离子基团。此外，还公开了一种包含潜在催化剂的环氧树脂组合物和使用该环氧树脂组合物的半导体器件。
• IDO Inhibitors
  申请人：Mautino Mario

  公开号：US20110053941A1

  公开（公告）日：2011-03-03

  Presently provided are methods for (a) modulating an activity of indoleamine 2,3-dioxygenase comprising contacting an indoleamine 2,3-dioxygenase with a modulation effective amount of a compound as described in one of the aspects described herein; (b) treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression in a subject in need thereof, comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; (c) treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; (d) enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent and a compound as described in one of the aspects described herein; (e) treating tumor-specific immunosuppression associated with cancer comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount of a compound as described in one of the aspects described herein; and (f) treating immunosuppression associated with an infectious disease, e.g., HIV-I infection, comprising administering an effective indoleamine 2,3-dioxygenase inhibiting amount a compound as described in one of the aspects described herein.

  目前提供以下方法：(a) 通过接触本文中描述的化合物的调节有效量与吲哚胺2,3-二氧化酶相互作用，从而调节吲哚胺2,3-二氧化酶的活性；(b) 治疗需要吲哚胺2,3-二氧化酶(IDO)介导的免疫抑制的患者，包括给予本文中描述的化合物的有效吲哚胺2,3-二氧化酶抑制剂量；(c) 治疗需要抑制吲哚胺-2,3-二氧化酶酶活性的医疗状况，包括给予本文中描述的化合物的有效吲哚胺2,3-二氧化酶抑制剂量；(d) 增强抗癌治疗的有效性，包括给予抗癌剂和本文中描述的化合物；(e) 治疗与癌症相关的肿瘤特异性免疫抑制，包括给予本文中描述的化合物的有效吲哚胺2,3-二氧化酶抑制剂量；(f) 治疗与传染病相关的免疫抑制，例如HIV-1感染，包括给予本文中描述的化合物的有效吲哚胺2,3-二氧化酶抑制剂量。
• OPTICAL FILM
  申请人：Motoyoshi Tetsuya

  公开号：US20110288261A1

  公开（公告）日：2011-11-24

  The object of this invention is to provide an optical film formed of a copolycarbonate having a desired chromatic dispersion and low photoelasticity and having excellent melt processability. The optical film comprises a copolycarbonate composed of 25 to 90 mol % of unit (A) of the following formula, wherein each of R 1 and R 2 is independently a hydrogen atom, a hydrocarbon group having 1 to 10 carbon atoms or a halogen atom, each of R 3 and R 4 is independently a hydrocarbon group having 1 to 10 carbon atoms, each of m and n is independently an integer of 0 to 4, and each of p and q is independently an integer of 0 or more, and 10 to 75 mol % of unit (B) of the following formula, wherein R a is a monocyclic or polycyclic alicyclic hydrocarbon group having 4 to 20 carbon atoms, the alicyclic hydrocarbon group may contain a hetero atom or may have a bridge structure, and q is 0 or 1, the optical film satisfying the following expression (1), R (450)< R (550)< R (650)  (1) wherein R(450), R(550) and R(650) are in-plane retardation values of the film at wavelengths of 450 nm, 550 nm and 650 nm.

  本发明的目的是提供一种光学薄膜，其由具有所需色散和低光弹性以及优异的熔融加工性的共聚碳酸酯形成。该光学薄膜包括由以下式中25至90摩尔％的(A)单元组成的共聚碳酸酯，其中R1和R2各自独立地为氢原子，具有1至10个碳原子的烃基或卤素原子，R3和R4各自独立地为具有1至10个碳原子的烃基，m和n各自独立地为0至4的整数，p和q各自独立地为0或更多的整数，并且由以下式中10至75摩尔％的(B)单元组成，其中Ra是具有4至20个碳原子的单环或多环脂环烃基，脂环烃基可以含有杂原子或具有桥式结构，q为0或1，该光学薄膜满足以下式(1)，R(450)