5-Ethyl-2-methoxy-3-(trifluoromethyl)pyridine | 1360943-32-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-Ethyl-2-methoxy-3-(trifluoromethyl)pyridine
• CAS: 1360943-32-3
• 化学式: C₉H₁₀F₃NO
• 分子量: 205.18
• InChiKey: HKUZZGWQPDQRKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS
  申请人：Lupin Limited

  公开号：US20190160045A1

  公开（公告）日：2019-05-30

  Disclosed are compounds of the general formula (I), wherein R1-R3 are as defined herein, for use as MALT1 inhibitors in the treatment of autoimmune and inflammatory diseases or disorders. Methods of synthesizing the compounds are also disclosed. Also disclosed are pharmaceutical compositions containing a compound of the invention and a method of treating a patient for an autoimmune or an inflammatory disease or disorder, for example, a cancer, by administering a compound of the invention.