2-(1.1-Dimethylbutyl)cyclohexanol | 80859-97-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(1.1-Dimethylbutyl)cyclohexanol
• 英文别名: 2-(2-Methylpentan-2-yl)cyclohexan-1-ol
• CAS: 80859-97-8
• 化学式: C₁₂H₂₄O
• 分子量: 184.322
• InChiKey: RENUEUBPXKJGNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS
  申请人：GLOBAL BLOOD THERAPEUTICS, INC.

  公开号：US20220396562A1

  公开（公告）日：2022-12-15

  The subject matter described herein is directed to ferroportin inhibitor compounds of Formula I or I′ and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.