2-hydroxy-14-methyl-1-cyclopentadecanone | 77634-69-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-hydroxy-14-methyl-1-cyclopentadecanone
• 英文别名: 2-Hydroxy-14-methylcyclopentadecan-1-one
• CAS: 77634-69-6
• 化学式: C₁₆H₃₀O₂
• 分子量: 254.413
• InChiKey: CFJCGVFZESZPLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Addition of ketones to alkenes
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP0976714A1

  公开（公告）日：2000-02-02

  The invention provides radical addition of ketone to alkene of the form: where R1 = alkyl R2 = H or alkyl n = 1 to 8 or where R3 = H or lower alkyl R4 = H or lower alkyl m = 2 to 8. The process can be used to produce precursors useful in the production of macrocyclic ketones, particularly muscone.

  该发明提供了将酮基加成到以下形式的烯烃中的基团：其中R1 = 烷基，R2 = H或烷基，n = 1到8，或其中R3 = H或低烷基，R4 = H或低烷基，m = 2到8。该方法可用于生产用于制造大环酮的前体，特别是肉麝香。
• PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP1102736A2

  公开（公告）日：2001-05-30
• [EN] PREPARATION OF MACROCYCLIC KETONES UTILISING ADDITION OF KETONES TO ALKENES<br/>[FR] PREPARATION DE CETONES MACROCYCLIQUES PAR ADDITION DES CETONES A DES ALCENES
  申请人：QUEST INT

  公开号：WO2000001648A2

  公开（公告）日：2000-01-13

  The invention provides a process for the preparation of macrocyclic ketones by a reaction sequence wherein one step is the radical addition of ketone to alkene of the form (1), where R3 = H or lower alkyl, R4 = H or lower alkyl, m = 4 to 8, or form (2), where R1 = alkyl, R2 = H or alkyl, n = 4 to 8. The process can be used to produce macrocyclic ketone mixtures, particularly those containing muscone which are useful in producing fragranced products.