methyl 4,6-dideoxy-2,3-di-O-methyl-4,6-methylimino-α-D-galactopyranoside | 62847-81-8

• 分子结构分类: 有机化合物 - 生物碱及其衍生物
• 英文名称: methyl 4,6-dideoxy-2,3-di-O-methyl-4,6-methylimino-α-D-galactopyranoside
• 英文别名: methyl O²,O³-dimethyl-4,6-methylazanediyl-α-D-4,6-dideoxy-galactopyranoside；(1R)-3c,4c,5t-trimethoxy-7-methyl-(1rH,6cH)-2-oxa-7-aza-bicyclo[4.2.0]octane
• CAS: 62847-81-8
• 化学式: C₁₀H₁₉NO₄
• 分子量: 217.265
• InChiKey: AKMJSQNMZQDRLD-KBDSZGMXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  15.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.16
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  methyl 4,6-O-isopropylidene-2,3-di-O-methyl-α-D-glucopyranoside 以 吡啶 、 乙醇 、 溶剂黄146 为溶剂， 反应 11.0h， 生成 methyl 4,6-dideoxy-2,3-di-O-methyl-4,6-methylimino-α-D-galactopyranoside
  参考文献：
  名称：

  Synthesis of monosaccharide-fused azetidines

  摘要：

  Primary amines reacted upon 4,6-ditosylates of glucopyranosides to give an azetidine ring fused on C-4 and C-6 of the pyranose ring. On the other hand, the 4,6-ditosylate of benzyl mannopyranoside led to the 4,6-diamino-4,6-dideoxy derivative in a good yield. All the compounds and their precursors were identified by H-1 and C-13 NMR spectroscopy. Assignments of proton signals were made unambiguously using homodecoupling experiments. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00015-3

文献信息

• Methyl 4,6-anhydro-4-deoxy-2,3-di-O-methyl-4-methyl-amino-α-d-galactopyranoside and related compounds
  作者：C. Richard Hall、Thomas D. Inch

  DOI：10.1016/s0008-6215(00)88095-7

  日期：1977.2