1-(1-hexadecyl-1H-1,2,3-triazol-4-yl)ethan-1-ol | 1263184-18-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(1-hexadecyl-1H-1,2,3-triazol-4-yl)ethan-1-ol
• CAS: 1263184-18-4
• 化学式: C₂₀H₃₉N₃O
• 分子量: 337.549
• InChiKey: UWJUZKNLSSGDCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.81
• 重原子数：
  24.0
• 可旋转键数：
  16.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  50.94
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  1-叠氮十六烷 、 3-丁炔-2-醇 在 cross-linked chitosan-Cu(I) 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 0.5h， 以96%的产率得到1-(1-hexadecyl-1H-1,2,3-triazol-4-yl)ethan-1-ol
  参考文献：
  名称：

  In situ cross-linked chitosan Cu(I) or Pd(II) complexes as a versatile, eco-friendly recyclable solid catalyst

  摘要：

  Herein we report a simple ultrasound-assisted procedure to synthesize solid supported Cu(I) and Pd(II) catalysts. We prepared cross-linked chitosan derivatives (CS-Cu, CS-Pd) by reacting hexamethylene diisocyanate and chitosan in the presence of the metal salt. The in situ polymerization in water under sonochemical conditions was extremely fast and efficient. The catalysts were characterized by FT-IR, XPS, ICP-MS. and TGA. The Cu(I)-loaded polyurethane/urea-bridged chitosan was used for the azide/alkyne [3 + 2] cycloaddition, while those bearing Pd(II) complexes were used for Suzuki cross-couplings. In both reactions these novel catalysts permitted the use of simpler procedures and the possibility to reuse the catalyst several times with a minimal lost in activity. Our polyurethane/urea-bridged CS-Cu and CS-Pd complexes are superior in term of activity, recyclability and ease of preparation when compared to the adsorbed Cu or Pd/chitosan catalysts. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2010.10.024