2-(3,5-dihydroxy-4-octanoylphenyl)acetic acid | 1374237-36-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(3,5-dihydroxy-4-octanoylphenyl)acetic acid
• CAS: 1374237-36-1
• 化学式: C₁₆H₂₂O₅
• 分子量: 294.348
• InChiKey: WBCMCIUHHJNPID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.27
• 重原子数：
  21.0
• 可旋转键数：
  9.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  94.83
• 氢给体数：
  3.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  辛酰氯 在 aluminum (III) chloride 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 13.0h， 生成 2-(3,5-dihydroxy-4-octanoylphenyl)acetic acid
  参考文献：
  名称：

  Total synthesis and allelopathic activity of cytosporones A-C

  摘要：

  The search for efficient, environmentally friendly herbicides has been the focus of numerous studies on the organic synthesis of compounds isolated from natural sources. Cytosporones, which are phenolic lipids isolated from fungi, exhibit noteworthy biological properties. This paper reports the preparation of cytosporones A-C from the same starting material through a short synthetic route, with good yields. All compounds were tested for allelopathic activity on lettuce (Lactuca sativa L) seeds. Cytosporone A and its methylated precursor showed remarkable allelopathic activity, inhibiting seed germination and plantule growth.

  DOI：

  10.1590/s0103-50532012000100018