4-异硫氰酸基-1-吡啶-3-基丁烷-1-酮 | 123529-37-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-异硫氰酸基-1-吡啶-3-基丁烷-1-酮
• 中文别名: 环(甘氨酰-精氨酰-甘氨酰-门冬氨酰-丝氨酰-门冬氨酰-丙氨酰)
• 英文名称: 1-Butanone, 4-isothiocyanato-1-(3-pyridinyl)-
• 英文别名: 4-isothiocyanato-1-pyridin-3-ylbutan-1-one
• CAS: 123529-37-3
• 化学式: C₁₀H₁₀N₂OS
• 分子量: 206.27
• InChiKey: CXXGJWMDYRATNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  74.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Method of modulating immune response by administration of immuno-activation agent
  申请人：Chiao Jen-Wei

  公开号：US20050070602A1

  公开（公告）日：2005-03-31

  The present invention is directed to a method of activating or augmenting an immune system of a mammal. The method comprises the step of administering a isothiocyanate (ITC) based agent, such as, N-acetylcysteine conjugate of phenethyl isothiocyanate (PEITC-NAC) or phenethyl isothiocyanate (PEITC), to a mammal in an amount sufficient to activate or augment the immune response in the mammal. The invention is further directed to a method of activating an antigen-specific immune response by administering to a subject an ITC based agent to in an amount sufficient to activate or augment the response of a B cell system or innate immunity to an antigen.
• US5114969A
  申请人：——

  公开号：US5114969A

  公开（公告）日：1992-05-19
• US5231209A
  申请人：——

  公开号：US5231209A

  公开（公告）日：1993-07-27