2-(11-Sulfanylundecoxy)ethanol | 165550-80-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(11-Sulfanylundecoxy)ethanol
• CAS: 165550-80-1
• 化学式: C₁₃H₂₈O₂S
• 分子量: 248.43
• InChiKey: XRRKURCPHRKZHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  16
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  30.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  S-[11-(2-hydroxyethoxy)undecyl] ethanethioate 在 盐酸 作用下， 以 甲醇 为溶剂， 以95%的产率得到2-(11-Sulfanylundecoxy)ethanol
  参考文献：
  名称：

  蛋白质在含有末端连接的寡聚（环氧乙烷）的表面上的吸附：使用自组装单层的模型系统

  摘要：

  本文报告了四种蛋白质 - 纤维蛋白原、溶菌酶、丙酮酸激酶和 RNA 酶 A 对金上自组装单层 (SAM) 的吸附研究。所检查的 SAM 源自结构为 HS(CH 2 ) 10 R 的硫醇，其中 R 是 CH 3 、CH 2 OH 和低聚（环氧乙烷）。含有足够大摩尔分数的链烷烃硫醇基团终止于低聚（环氧乙烷）链的单层抵抗所有四种蛋白质的动力学不可逆、非特异性吸附。较长的低聚（环氧乙烷）链在单层中的较低摩尔分数下具有抗性。对蛋白质吸附的抵抗力随着低聚（环氧乙烷）链的长度而增加：阻止吸附的链的最小摩尔分数与 n -0.4 成正比，其中 n 表示每条链的环氧乙烷单元数

  DOI：

  10.1021/ja00076a032

文献信息

• Continuous Flow Bioreactor for Magnetically Stabilized Three-Dimensional Tissue Culture
  申请人：Lambert Christopher R.

  公开号：US20130203145A1

  公开（公告）日：2013-08-08

  The invention provides methods for rapid, continuous generation of cells and cell products using magnetically stabilized three-dimensional tissue culture. The invention also pertains to a continuous flow self-regulating closed system bioreactor system for magnetically stabilized three-dimensional tissue culture. The methods described here do not use traditional solid scaffolding for cell culture.
• CHEMICALLY-DEFINED ARRAYS FOR SCREENING CELL-SUBSTRATE INTERACTIONS
  申请人：Koepsel Justin T.

  公开号：US20130296177A1

  公开（公告）日：2013-11-07

  Patterned SAM arrays and methods of preparing patterned SAM arrays are disclosed. Advantageously, the methods used to prepare the patterned SAM arrays allow for controlling SAM spot-to-spot conditions such as ligand identity and ligand density, which allows for preparing a wide range of SAM spots in a single array format. Additionally, the patterned SAM arrays of the present disclosure support the culture of a range of cell types. The patterned SAM arrays offer the ability to rapidly screen substrate components for influencing cell attachment, spreading, proliferation, migration, and differentiation.
• US8642516B2
  申请人：——

  公开号：US8642516B2

  公开（公告）日：2014-02-04
• [EN] CONTINUOUS FLOW BIOREACTOR FOR MAGNETICALLY STABILIZED THREE-DIMENSIONAL TISSUE CULTURE<br/>[FR] BIORÉACTEUR À ÉCOULEMENT CONTINU POUR LA CULTURE DE TISSU EN TROIS DIMENSIONS STABILISÉE MAGNÉTIQUEMENT
  申请人：WORCESTER POLYTECH INST

  公开号：WO2011112601A2

  公开（公告）日：2011-09-15

  The invention provides methods for rapid, continuous generation of cells and cell products using magnetically stabilized three-dimensional tissue culture. The invention also pertains to a continuous flow self-regulating closed system bioreactor system for magnetically stabilized three-dimensional tissue culture. The methods described here do not use traditional solid scaffolding for cell culture.