[(4-hydroxymethylphenyl)-methyl] 2,3,4,6-tetra-O-allyl-β-D-gluco-hexopyranoside | 252060-83-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(4-hydroxymethylphenyl)-methyl] 2,3,4,6-tetra-O-allyl-β-D-gluco-hexopyranoside
• CAS: 252060-83-6
• 化学式: C₂₆H₃₆O₇
• 分子量: 460.568
• InChiKey: DCNKXTJJECVFFS-WSGIOKLISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.34
• 重原子数：
  33.0
• 可旋转键数：
  17.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  75.61
• 氢给体数：
  1.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  [(4-hydroxymethylphenyl)-methyl] 2,3,4,6-tetra-O-allyl-β-D-gluco-hexopyranoside 、 叔丁基二甲硅基三氟甲磺酸酯 在 吡啶 作用下， 以 乙腈 为溶剂， 以65%的产率得到{[4-(tert-butyldimethylsiloxymethyl)-phenyl]-methyl} 2,3,4,6-tetra-O-allyl-β-D-gluco-hexopyranoside
  参考文献：
  名称：

  Synthesis of Selectively Functionalized Carbosilane Dendrimers with a Carbohydrate Core

  摘要：

  [GRAPHICS]First-generation members of a novel family of dendrimers schematically shown above have been synthesized. They display carbohydrate-centered carbosilanes in which one functional group (FG) is discriminated from the others. This will eventually allow their utilization in the synthesis of labeled carbosilanes or as selectively functionalized scaffolds for the preparation of multivalent glycomimetics.

  DOI：

  10.1021/ol9910619
• 作为产物：
  描述：

  [(4-methoxycarbonylphenyl)methyl] 2,3,4,6=tetra-O-allyl-β-D-glucopyranoside 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 0.75h， 以100%的产率得到[(4-hydroxymethylphenyl)-methyl] 2,3,4,6-tetra-O-allyl-β-D-gluco-hexopyranoside
  参考文献：
  名称：

  Synthesis of Selectively Functionalized Carbosilane Dendrimers with a Carbohydrate Core

  摘要：

  [GRAPHICS]First-generation members of a novel family of dendrimers schematically shown above have been synthesized. They display carbohydrate-centered carbosilanes in which one functional group (FG) is discriminated from the others. This will eventually allow their utilization in the synthesis of labeled carbosilanes or as selectively functionalized scaffolds for the preparation of multivalent glycomimetics.

  DOI：

  10.1021/ol9910619