(S)-4-iodo-1-(6-(2-tert-butoxycarbonylamino-3-phenylpropanoyloxy)hexyloxy)benzene | 1046451-11-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-4-iodo-1-(6-(2-tert-butoxycarbonylamino-3-phenylpropanoyloxy)hexyloxy)benzene
• 英文别名: (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid 6-(4-iodophenoxy)hexyl ester；6-(4-iodophenoxy)hexyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoate
• CAS: 1046451-11-9
• 化学式: C₂₆H₃₄INO₅
• 分子量: 567.464
• InChiKey: LZCKGSIBMFEIKG-QHCPKHFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  33
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  73.9
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (S)-4-iodo-1-(6-(2-tert-butoxycarbonylamino-3-phenylpropanoyloxy)hexyloxy)benzene 、 5,5''-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2':5',2''-terthiophene 在 四(三苯基膦)钯 、 sodium carbonate 、 silver(l) oxide 作用下， 以 1,4-二氧六环 为溶剂， 以85%的产率得到(S,S)-5,5''-bis-(4-(6-(2-tert-butoxycarbonylamino-3-phenylpropanoyloxy)hexyloxy)phenyl)-[2,2':5',2'']-terthiophene
  参考文献：
  名称：

  Synthesis of d-glucose and l-phenylalanine substituted phenylene–thiophene oligomers

  摘要：

  Phenylene-thiophene oligomers bearing peracetylated beta-D-glucose or N-BOC-L-phenylalanine as chiral substituents were synthesized in good yields by a versatile protocol based on the Suzuki-Miyaura cross-coupling reaction. Aryl iodides bearing the chiral biomolecules as substituents efficiently reacted with pinacol boronates of bi- or terthiophenes leading to the bio-functionalized oligomers in good yields. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.11.004
• 作为产物：
  描述：

  6-溴正己醇 在 4-二甲氨基吡啶 、 异丙烯基氯甲酸酯 、 三乙胺 、 potassium hydroxide 作用下， 以 二氯甲烷 、 二甲基亚砜 为溶剂， 反应 9.67h， 生成 (S)-4-iodo-1-(6-(2-tert-butoxycarbonylamino-3-phenylpropanoyloxy)hexyloxy)benzene
  参考文献：
  名称：

  Synthesis of d-glucose and l-phenylalanine substituted phenylene–thiophene oligomers

  摘要：

  Phenylene-thiophene oligomers bearing peracetylated beta-D-glucose or N-BOC-L-phenylalanine as chiral substituents were synthesized in good yields by a versatile protocol based on the Suzuki-Miyaura cross-coupling reaction. Aryl iodides bearing the chiral biomolecules as substituents efficiently reacted with pinacol boronates of bi- or terthiophenes leading to the bio-functionalized oligomers in good yields. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.11.004

文献信息

• Organic thin film transistors comprising thienyl oligomers and their use as gaseous phase sensors
  申请人：Babudri Francesco

  公开号：US20100140597A1

  公开（公告）日：2010-06-10

  This invention pertains to gaseous analytes sensor devices comprising organic thin film transistor and, in particular sensors able to perform the enantiomeric discrimination of gaseous analytes. The organic thin films are characterized by comprising a compound of formula (I).

  本发明涉及气体分析物传感器装置，包括有机薄膜晶体管，特别是能够执行气体分析物对映异构体鉴别的传感器。有机薄膜的特征是包含公式（I）的化合物。
• WO2008/96239
  申请人：——

  公开号：——

  公开（公告）日：——
• US8461354B2
  申请人：——

  公开号：US8461354B2

  公开（公告）日：2013-06-11
• [EN] ORGANIC THIN FILM TRANSISTORS COMPRISING THIENYL OLIGOMERS AND THEIR USE AS GASEOUS PHASE SENSORS<br/>[FR] TRANSISTORS À FILM MINCE ORGANIQUE COMPRENANT DES OLIGOMÈRES DE THIÉNYLE ET LEUR UTILISATION EN TANT QUE DÉTECTEURS EN PHASE GAZEUSE
  申请人：UNIV BARI

  公开号：WO2008096239A1

  公开（公告）日：2008-08-14

  [EN] This invention pertains to gaseous analytes sensor devices comprising organic thin film transistor and, in particular, sensors able to perform the enantiomeric discrimination of gaseous analytes. The organic thin films are characterized by comprising a compound of formula (I).
  [FR] La présente invention a pour objet des dispositifs détecteurs d'analytes gazeux comprenant un transistor à film mince organique et, en particulier, des détecteurs capables d'effectuer la discrimination énantiomérique des analytes gazeux. Les films minces organiques sont caractérisés en ce qu'ils comprennent un composé de formule (I).