2-methyl-1-vinylpyridinium chloride | 1143517-95-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-methyl-1-vinylpyridinium chloride
• 英文别名: 1-ethenyl-2-methylpyridin-1-ium;chloride
• CAS: 1143517-95-6
• 化学式: C₈H₁₀N*Cl
• 分子量: 155.627
• InChiKey: UHLFIEFVOSFSGQ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.61
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-methyl-1-vinylpyridinium chloride 、 三苯基膦 以 乙腈 为溶剂， 反应 32.0h， 生成 [2-(6-methylpyridine-2-yl)ethyl]triphenylphosphonium chloride 、 1,2-bis(triphenylphosphonio)ethane dichloride
  参考文献：
  名称：

  Features of the reaction of 2,3-dihalopropanoic acids with pyridines and nucleophilic addition to N-vinylpyridinium salts

  摘要：

  The example of vinylpyridinium salts to establish for the first time the possibility of nucleophilic addition to the vinyl group in quaternary ammonium salts, which provides evidence against the concept that such reactions involve d orbitals. The nucleophilic addition reaction was accomplished with triphenylphosphine and pyridine. In the latter case, the suggested reaction scheme was confirmed by the observation of the Wittig reaction under the action of carbon dioxide and the Stevens reaggangement involving the double bond of the pyridinium ring and migrating 2-phosphonioethyl group. Procedures for preparing the starting vinylpyridinium salts. Reaction schemes were siggested.

  DOI：

  10.1134/s107036320807030x
• 作为产物：
  描述：

  碳酸甲丙酯 、 2,3-二氯丙酸 以 乙腈 为溶剂， 反应 60.0h， 以6.4%的产率得到
  参考文献：
  名称：

  Features of the reaction of 2,3-dihalopropanoic acids with pyridines and nucleophilic addition to N-vinylpyridinium salts

  摘要：

  The example of vinylpyridinium salts to establish for the first time the possibility of nucleophilic addition to the vinyl group in quaternary ammonium salts, which provides evidence against the concept that such reactions involve d orbitals. The nucleophilic addition reaction was accomplished with triphenylphosphine and pyridine. In the latter case, the suggested reaction scheme was confirmed by the observation of the Wittig reaction under the action of carbon dioxide and the Stevens reaggangement involving the double bond of the pyridinium ring and migrating 2-phosphonioethyl group. Procedures for preparing the starting vinylpyridinium salts. Reaction schemes were siggested.

  DOI：

  10.1134/s107036320807030x

文献信息

• PVA gel
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0263647A2

  公开（公告）日：1988-04-13

  A hydrated PVA gel is impregnated with a polymer of an ethylenically-unsaturated, water-soluble ionic monomer. The hydrated gel is reversibly-dehydratable. The product is produced by polymerisation of the monomer in situ within the gel.

  水合 PVA 凝胶中浸渍有乙烯不饱和水溶性离子单体聚合物。 水合凝胶具有可逆脱水性。 产品是由凝胶中的单体原位聚合而成。
• EP1613276A1
  申请人：——

  公开号：EP1613276A1

  公开（公告）日：2006-01-11
• NANOPARTICULATE COMPOSITIONS HAVING A PEPTIDE AS A SURFACE STABILIZER
  申请人：Elan Pharma International Limited

  公开号：EP1686962A2

  公开（公告）日：2006-08-09
• COMPOSITION COMPRISING ANTIBODIES AND METHODS OF USING THE SAME FOR TARGETED NANOPARTICULATE ACTIVE AGENT DELIVERY
  申请人：Elan Pharma International Limited

  公开号：EP1689442A2

  公开（公告）日：2006-08-16
• NANOPARTICULATE QUINAZOLINE DERIVATIVE FORMULATIONS
  申请人：Elan Pharma International Limited

  公开号：EP1871345A1

  公开（公告）日：2008-01-02