3,5-dimethyl-5'-phenyl-1H-1,4'-bipyrazole | 1251744-63-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3,5-dimethyl-5'-phenyl-1H-1,4'-bipyrazole
• CAS: 1251744-63-4
• 化学式: C₁₄H₁₄N₄
• 分子量: 238.292
• InChiKey: DAMQEHKZNZDZQH-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  (Z)-3-dimethylamino-2-(3,5-dimethyl-1H-1-pyrazolyl)-1-phenyl-2-propen-1-one 在 一水合肼 作用下， 以 乙醇 为溶剂， 反应 5.0h， 以71%的产率得到3,5-dimethyl-5'-phenyl-1H-1,4'-bipyrazole
  参考文献：
  名称：

  Highly regioselective synthesis of novel 1,4'-bipyrazoles

  摘要：

  Novel 1,4'-bipyrazoles were synthesized via highly regioselective cyclocondensation reactions of b-dimethylaminoenones with hydrazine monohydrate, tert-butylhydrazine hydrochloride, phenylhydrazine hydrochloride or carboxymethylhydrazine. X-ray diffraction technique was used in the elucidation of the regiochemistry of the beta-dimethylaminoenaminones and of the 1,4'-bipyrazoles. 1,4'-Bipyrazolylisoxazoles were also reported.

  DOI：

  10.1590/s0103-50532010000200008