methyl (2S,4S)-4-{[bis(benzyloxy)phosphoryl]methyl}-5-oxotetrahydrofuran-2-carboxylate | 1312438-91-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: methyl (2S,4S)-4-{[bis(benzyloxy)phosphoryl]methyl}-5-oxotetrahydrofuran-2-carboxylate
• 英文别名: methyl (2S,4S)-4-[bis(phenylmethoxy)phosphorylmethyl]-5-oxooxolane-2-carboxylate
• CAS: 1312438-91-7
• 化学式: C₂₁H₂₃O₇P
• 分子量: 418.383
• InChiKey: NPIXOTFSCYEZOT-MOPGFXCFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  29
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  88.1
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• [EN] PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS<br/>[FR] INHIBITEURS D'ANTIGÈNES MEMBRANAIRES SPÉCIFIQUES DE LA PROSTATE
  申请人：BAYER SCHERING PHARMA AG

  公开号：WO2011073286A1

  公开（公告）日：2011-06-23

  This invention relates to novel compounds suitable for labelling by 18F and the corresponding 18F labelled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by positron emission tomography (PET).

  这项发明涉及适合用18F标记的新化合物，以及相应的18F标记化合物本身，其19F-氟化类似物及其作为参考标准的用途，制备这种化合物的方法，包含这种化合物的组合物，包含这种化合物或组合物的试剂盒以及用于正电子发射断层扫描（PET）的这种化合物、组合物或试剂盒的用途。
• PROSTATE SPECIFIC MEMBRANE ANTIGEN INHIBITORS
  申请人：Graham Keith

  公开号：US20120328518A1

  公开（公告）日：2012-12-27

  This invention relates to novel compounds suitable for labelling by 18 F and the corresponding 18 F labelled compounds themselves, 19 F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by positron emission tomography (PET).

  本发明涉及适用于18F标记的新化合物以及相应的18F标记化合物、19F-氟化类似物及其作为参考标准的用途，制备这些化合物的方法，包含这些化合物的组合物、包含这些化合物或组合物的试剂盒以及利用这些化合物、组合物或试剂盒进行正电子发射断层扫描（PET）诊断成像的用途。
• Prostate specific membrane antigen inhibitors
  申请人：Bayer Schering Pharma Aktiengesellschaft

  公开号：EP2338892A1

  公开（公告）日：2011-06-29

  This invention relates to novel compounds suitable for labelling by 18F and the corresponding 18F labelled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by positron emission tomography (PET).

  本发明涉及适用于 18F 标记的新型化合物及其相应的 18F 标记化合物本身、19F-氟化类似物及其作为参考标准的用途、制备此类化合物的方法、包含此类化合物的组合物、包含此类化合物或组合物的试剂盒以及此类化合物、组合物或试剂盒在正电子发射断层扫描（PET）诊断成像中的用途。