| 1402139-18-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• CAS: 1402139-18-7
• 化学式: C₂₃H₁₈N₂O₆
• 分子量: 418.406
• InChiKey: URDGCZHUKGJBDI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.01
• 重原子数：
  31.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  110.73
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  、 氰化四丁基铵 以 乙腈 为溶剂， 反应 0.01h， 生成
  参考文献：
  名称：

  Coumarin?indanedione conjugate as a doubly activated Michael addition type probe for the colorimetric and ratiometric fluorescent detection of cyanide

  摘要：

  A coumarin-indanedione conjugate as an activated Michael addition type probe was prepared for cyanide ion detection. The colorimetric and ratiometric fluorescent response of the probe to cyanide ion is due to the Michael addition of cyanide to the doubly activated Michael receptor of the probe which blocks an intramolecular charge transfer process. The probe displays a fast response to cyanide ion at room temperature, and a maximal ratiometric fluorescent signal is achieved in the presence of only 2 equivalents of cyanide ion. Moreover, competitive species did not induce any significant changes both in color and emission intensity ratio (I-485/I-609), demonstrating the high selectivity of the probe to cyanide. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.03.025
• 作为产物：
  描述：

  4-nitro-1H-indene-1,3(2H)-dione 、 2H-1-苯并吡喃-3-羧醛, 7-(二乙基氨基)-2-氧代- 在 哌啶 作用下， 以 乙醇 为溶剂， 以48%的产率得到
  参考文献：
  名称：

  Coumarin?indanedione conjugate as a doubly activated Michael addition type probe for the colorimetric and ratiometric fluorescent detection of cyanide

  摘要：

  A coumarin-indanedione conjugate as an activated Michael addition type probe was prepared for cyanide ion detection. The colorimetric and ratiometric fluorescent response of the probe to cyanide ion is due to the Michael addition of cyanide to the doubly activated Michael receptor of the probe which blocks an intramolecular charge transfer process. The probe displays a fast response to cyanide ion at room temperature, and a maximal ratiometric fluorescent signal is achieved in the presence of only 2 equivalents of cyanide ion. Moreover, competitive species did not induce any significant changes both in color and emission intensity ratio (I-485/I-609), demonstrating the high selectivity of the probe to cyanide. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.03.025