2-((N,N'-dimethylamino)methyloxy)cyclohexanol | 1240486-19-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-((N,N'-dimethylamino)methyloxy)cyclohexanol
• 英文别名: 2-[(dimethylamino)methoxy]cyclohexan-1-ol
• CAS: 1240486-19-4
• 化学式: C₉H₁₉NO₂
• 分子量: 173.255
• InChiKey: LQIUFNREEATYDY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.83
• 重原子数：
  12.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.7
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 1,2-环己二醇 、 二甲胺 以 甲苯 为溶剂， 以90.5%的产率得到2-((N,N'-dimethylamino)methyloxy)cyclohexanol
  参考文献：
  名称：

  Synthesis and examination of antimicrobial properties of aminomethylated derivatives C6–C7 of alicyclic diols

  摘要：

  Synthesis of C-6-C-7 alicyclic diols was studied by a catalytic oxidation of cyclohexene, norbornene and their methyl derivatives in the presence of heterogenized molybdenum-containing catalysts. By a triple condensation of the diols with formaldehyde and secondary amines a synthesis of their aminomethylated derivatives with various substituents at nitrogen atom was examined. Antimicrobial properties of the synthesized amino alcohols in M-10 oil as additives with fungicidal and bactericidal activities were studied.

  DOI：

  10.1134/s1070427209070180