1-{1,4-Dioxaspiro[4.5]decan-2-ylmethyl}guanidine hydroiodide | 1443980-00-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-{1,4-Dioxaspiro[4.5]decan-2-ylmethyl}guanidine hydroiodide
• 英文别名: 2-(1,4-dioxaspiro[4.5]decan-3-ylmethyl)guanidine;hydroiodide
• CAS: 1443980-00-4
• 化学式: C10H20IN3O2
• mdl: MFCD24842892
• 分子量: 341.19
• InChiKey: UJFWFEOFSBQPSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.68
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  82.9
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• [EN] COMPOUNDS FOR USE IN THE TREATMENT OF SYNUCLEINOPATHIES<br/>[FR] COMPOSÉS DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT DE SYNUCLÉINOPATHIES
  申请人：SOM INNOVATION BIOTECH S A

  公开号：WO2021191417A1

  公开（公告）日：2021-09-30

  The present invention relates to a compound selected from the group consisting of of N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H- pyrazol-5-yl)thiophene-2-carboxamide, [2-(2,6-dichloroanilino)-4,5-dihydroimidazol-1- yl]-phenylmethanone, 2-amino-5-bromo-4-phenyl-1H-pyrimidin-6-one, N- (diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide and 2-(1,4- dioxaspiro[4.5]decan-2-ylmethyl)guanidin, or a pharmaceutically acceptable salt thereof and combinations comprising at least one of said compounds, for use in the treatment and/or prevention of synucleinopathies.