(3Z)-3-(cyclohexylmethylidene)oxolan-2-one | 66909-50-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: (3Z)-3-(cyclohexylmethylidene)oxolan-2-one
• CAS: 66909-50-0
• 化学式: C₁₁H₁₆O₂
• 分子量: 180.247
• InChiKey: XKZHXNALSPYTPC-NTMALXAHSA-N

物化性质

• 沸点：
  131-134 °C(Press: 1 Torr)
• 密度：
  1.155±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  dilithium;4-sulfido-2,3-dihydrofuran-5-olate 以59%的产率得到
  参考文献：
  名称：

  TANAKA K.; UNEME H.; YAMAGISHI N.; ONO N.; KAJI A., CHEM. LETT., 1978, NO 6, 653-656

  摘要：

  DOI：

文献信息

• Total synthesis of the ent-clerodane diterpenoids (±)-isolinaridiol and (±)-isolinaridiol diacetate
  作者：Edward Piers、John S. M. Wai

  DOI：10.1039/c39880001245

  日期：——

  A previously described mixture of bicyclo[4.4.0]decanecarbonitriles [(4) and (5)] was converted, via a nine-step sequence of reactions, into (±)-isolinaridiol (3), which was readily transformed into the corresponding diacetate (2).

  通过九步反应序列，将先前描述的双环[4.4.0]癸碳腈[（4）和（5）]混合物转化为（±）-异芳基二醇（3），可轻松将其转化为相应的双乙酸盐（2）。
• Stereoselective Synthesis of (<i>E</i>)- or (<i>Z</i>)-α-Alkylidene-γ-butyrolactone from γ-Butyrolactone and Bis[ethoxy(thiocarbonyl)] Disulfide and Mechanistic Studies of the Effect of Metal Complexes on the Stereoselection
  作者：Syuichi Matsui

  DOI：10.1246/bcsj.60.1853

  日期：1987.5

  with an aldehyde to afford exclusively (E)-α-alkylidene-γ-butyrolactone. Interestingly, when the reaction was quenched below −20 °C or when it was carried out in the presence of metal complex such as zinc chloride, copper(I) iodide, or tributyltin chloride, (Z)-α-alkylidene-γ-butyrolactone was obtained as the major product. The stereoselectivity of this reaction was sensitive to the reaction temperature

  在 2.2 当量二异丙基氨基锂 (LDA) 存在下，用双 [乙氧基（硫代羰基）] 二硫化物处理 γ-丁内酯，生成 O-乙基 S-（四氢-2-氧代-3-呋喃基）二硫代碳酸酯的烯醇锂，其反应用醛生成仅 (E)-α-亚烷基-γ-丁内酯。有趣的是，当反应在 -20 °C 以下猝灭或在金属络合物（如氯化锌、碘化铜（I）或氯化三丁基锡、（Z）-α-亚烷基-γ-丁内酯）存在下进行时作为主要产品获得。该反应的立体选择性对反应温度和所用金属阳离子敏感。
• A SIMPLE, STEREOCONTROLLED SYNTHESIS OF α-ALKYLIDENE-γ-BUTYROLACTONES
  作者：Kazuhiko Tanaka、Norikazu Tamura、Aritsune Kaji

  DOI：10.1246/cl.1980.595

  日期：1980.5.5

  Treatment of γ-butyrolactone with bis[methoxy(thiocarbonyl)] disulfide in the presence of 2.2 equivalents of lithium diisopropylamide followed by the addition of aldehydes gave predominantly (E)-α-alkylidene-γ-butyrolactones. In contrast, when the reaction was carried out in the presence of metal salt such as cuprous iodide or zinc chloride, (Z)-α-alkylidene-γ-butyrolactone was obtained as the major

  在2.2当量二异丙基氨基锂存在下用双[甲氧基（硫代羰基）]二硫化物处理γ-丁内酯，然后加入醛，主要得到（E）-α-亚烷基-γ-丁内酯。相反，当反应在金属盐如碘化亚铜或氯化锌的存在下进行时，主要产物是(Z)-α-亚烷基-γ-丁内酯。
• Components and catalysts for the polymerization of olefins
  申请人：Gulevich Yuri

  公开号：US20090118446A1

  公开（公告）日：2009-05-07

  The present invention relates to a solid catalyst component for the polymerization of olefins CH 2 ═CHR in which R is hydrogen or a hydrocarbon radical with 1-12 carbon atoms, comprising Mg, Ti, halogen and an electron donor selected from γ-butyrolactone derivatives of a particular formula. Said catalyst components, when used in the polymerization of olefins and in particular of propylene, are capable to give polymers in high yields and with high isotactic index expressed in terms of high xylene insolubility.

  本发明涉及一种用于聚合烯烃CH2═CHR（其中R为氢或1-12个碳原子的碳氢基团）的固体催化剂组分，包括Mg、Ti、卤素和从特定公式的γ-丁内酯衍生物中选择的电子给体。当在聚合烯烃，特别是丙烯的聚合中使用该催化剂组分时，能够高产高异构指数聚合物，表现为高二甲苯不溶性。
• Total Synthesis of (±)-Hedychilactone B:  Stepwise Allenoate Diene Cycloaddition To Prepare Trimethyldecalin Systems
  作者：Michael E. Jung、Masayuki Murakami

  DOI：10.1021/ol062811z

  日期：2007.2.1

  The total synthesis of the diterpene hedychilactone B 1 is reported. The exo adduct 4x, the major product of the stepwise [4+2] cycloaddition of the diene 2 and the allenoate 3, has been converted into 1 via 7 steps, among them a key nonconjugative hydrolysis of a gamma-methylene silyl enol ether and an E-selective olefination.