1-[1,1,2-trifluoro-2-(trifluoromethoxy)ethyl]-1H-imidazole | 943522-68-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-[1,1,2-trifluoro-2-(trifluoromethoxy)ethyl]-1H-imidazole
• 英文别名: 1-(1,1,2-trifluoro-2-trifluoromethoxyethyl)imidazole；1-[1,1,2-trifluoro-2-(trifluoromethoxy)ethyl]imidazole
• CAS: 943522-68-7
• 化学式: C₆H₄F₆N₂O
• 分子量: 234.101
• InChiKey: TYBWWMPZQKTXSM-UHFFFAOYSA-N

物化性质

• 沸点：
  195.8±40.0 °C(Predicted)
• 密度：
  1.55±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  27
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  咪唑 、 三氟甲基三氟乙烯基醚 在 sodium hydride 作用下， 以 melt 、 mineral oil 为溶剂， 反应 0.08h， 以93%的产率得到1-[1,1,2-trifluoro-2-(trifluoromethoxy)ethyl]-1H-imidazole
  参考文献：
  名称：

  各种唑类与全氟甲基乙烯基醚的加成反应

  摘要：

  已证明全氟甲基乙烯基醚与各种唑类（吡咯、咪唑、吡唑、吲哚、苯并三唑、咔唑和三唑的衍生物）的加成反应。反应条件取决于杂环的熔点和亲核性。所得产物具有水解和热稳定性，具有高度亲脂性，可作为不同生物活性化合物合成的有用前体。

  DOI：

  10.1007/s10593-021-02965-9

文献信息

• FLUORINE-CONTAINING POLYMER HAVING HETEROAROMATIC RING
  申请人：Komatsu Yuzo

  公开号：US20090105400A1

  公开（公告）日：2009-04-23

  There is provided a fluorine-containing polymer having an ionic group which has a heteroaromatic ring and is useful as a material comprising various heteroaromatic ring compounds having a stable fluorine-containing heteroaromatic ring, and further a fluorine-containing polymer having a heteroaromatic ring which is useful as a starting material of the above-mentioned polymer or a curing agent. Also, there is provided a fluorine-containing polymer having a heteroaromatic ring such as imidazole in its side chain, a polymer salt thereof, and a polymer composition comprising such a polymer and a polymer salt and a nano filler.

  提供了一种含氟聚合物，其具有带有杂环芳香环的离子基，并且可用作由稳定的含氟杂环芳香环化合物组成的材料，还提供了一种具有杂环芳香环的含氟聚合物，可用作上述聚合物或固化剂的起始材料。此外，还提供了一种具有杂环芳香环（如咪唑）的含氟聚合物及其聚合物盐，以及包含该聚合物、聚合物盐和纳米填料的聚合物组合物。
• PROCESS FOR PREPARING HETEROAROMATIC RING COMPOUND HAVING N-Rf GROUP
  申请人：Komatsu Yuzo

  公开号：US20100222598A1

  公开（公告）日：2010-09-02

  There is provided a preparation process in which a N—H group of a heteroaromatic ring compound having a N—H group in its ring is converted directly to a N—Rf group at a high reaction efficiency without using a catalyst. The preparation process is a process for preparing a compound comprising a heteroaromatic ring structure having a N—Rf group (—Rf is a fluorine-containing organic group) in its ring and is characterized in that the heteroaromatic ring compound having a N—H group in its ring is allowed to react with fluoroalkene in the absence of an alkali metal.

  提供了一种制备过程，其中在不使用催化剂的情况下，将具有其环中的N-H基团的杂环芳香化合物的N-H基团直接转化为高反应效率的N-Rf基团。该制备过程是制备具有其环中的N-Rf基团（-Rf是含氟有机基团）的杂环芳香环结构化合物的过程，并且其特征在于，在没有碱金属的情况下，将具有其环中的N-H基团的杂环芳香化合物与氟代烯烃发生反应。
• METHOD FOR PRODUCTION OF HETEROAROMATIC RING COMPOUND HAVING N-Rf GROUP
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP1975157A1

  公开（公告）日：2008-10-01

  There is provided a preparation process in which a N-H group of a heteroaromatic ring compound having a N-H group in its ring is converted directly to a N-Rf group at a high reaction efficiency without using a catalyst. The preparation process is a process for preparing a compound comprising a heteroaromatic ring structure having a N-Rf group (-Rf is a fluorine-containing organic group) in its ring and is characterized in that the heteroaromatic ring compound having a N-H group in its ring is allowed to react with fluoroalkene in the absence of an alkali metal.

  本发明提供了一种制备工艺，在该工艺中，环中具有 N-H 基团的杂芳香族环状化合物的 N-H 基团可直接转化为 N-Rf 基团，且反应效率高，无需使用催化剂。该制备工艺是一种制备包含杂芳香族环结构的化合物的工艺，该化合物的环中具有一个 N-Rf 基团（-Rf 是含氟有机基团），其特征在于让环中具有一个 N-H 基团的杂芳香族环化合物在没有碱金属的情况下与氟烯烃反应。
• FLUORINE-CONTAINING POLYMER CONTAINING HETEROAROMATIC RING
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP1983008A1

  公开（公告）日：2008-10-22

  There is provided a fluorine-containing polymer having an ionic group which has a heteroaromatic ring and is useful as a material comprising various heteroaromatic ring compounds having a stable fluorine-containing heteroaromatic ring, and further a fluorine-containing polymer having a heteroaromatic ring which is useful as a starting material of the above-mentioned polymer or a curing agent. Also, there is provided a fluorine-containing polymer having a heteroaromatic ring such as imidazole in its side chain, a polymer salt thereof, and a polymer composition comprising such a polymer and a polymer salt and a nano filler.

  本发明提供了一种具有离子基团的含氟聚合物，该聚合物具有杂芳香族环，可用作由具有稳定的含氟杂芳香族环的各种杂芳香族环化合物组成的材料，还提供了一种具有杂芳香族环的含氟聚合物，该聚合物可用作上述聚合物的起始材料或固化剂。此外，还提供了一种在侧链中具有咪唑等杂芳环的含氟聚合物、其聚合物盐，以及包含这种聚合物和聚合物盐以及纳米填料的聚合物组合物。
• ACTUATOR ELEMENT
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：EP1981034A1

  公开（公告）日：2008-10-15

  There is provided an actuator element which can be driven at low voltages, is operated stably in air and in vacuo with a quick response, exhibits a large degree of displacement and a large displacement force, has high mechanical strength including flexibility, thus giving long-term durability for repeated use, can be produced by a very simple method, can be formed into a small size because of a simple structure, and can be put into practical use in wide applications. The actuator element is comprised of an ion-conducting layer for an actuator element comprising (I) a fluorine-containing polymer having functional group and (II) an ionic liquid, in which the fluorine-containing polymer having functional group is a polymer having functional group selected from the group consisting of -OH, -COOH, -COOR, -CN, iodine atom, epoxy group and (meth)acryloyl group in a polymer side chain and/or at an end of a polymer trunk chain, and an electrode layer comprising (I) the fluorine-containing polymer having functional group, (II) an ionic liquid and (III) an electroconductive nano-filler.

  本发明提供了一种可在低电压下驱动的致动器元件，它可在空气和真空中稳定运行且反应迅速，具有较大的位移量和较大的位移力，具有较高的机械强度和柔韧性，因此可反复长期使用，可通过非常简单的方法生产，因结构简单而可制成较小的尺寸，并可在广泛的应用中投入实际使用。该致动器元件由用于致动器元件的离子传导层组成，该离子传导层由 (I) 具有官能团的含氟聚合物和 (II) 离子液体构成，其中具有官能团的含氟聚合物是具有选自 -OH、-COOH、-COOR、-CN、碘原子、环氧基和（甲基）丙烯酰基组成的聚合物侧链和/或聚合物主链的末端，以及电极层，电极层包括（I）具有官能团的含氟聚合物、（II）离子液体和（III）导电纳米填料。