8-<3H>-Adenosin | 32603-44-4

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷
• 英文名称: 8-<3H>-Adenosin
• 英文别名: [8-³H]-adenosine；(2R,3R,4S,5R)-2-(6-amino-8-tritiopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• CAS: 32603-44-4
• 化学式: C₁₀H₁₃N₅O₄
• 分子量: 269.236
• InChiKey: OIRDTQYFTABQOQ-BENJYUDCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  140
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• DIHYDROOXADIAZINONES
  申请人：Bayer Aktiengesellschaft

  公开号：US20200369633A1

  公开（公告）日：2020-11-26

  The present invention provides dihydrooxydiazinone compounds of general formula (I): in which R 1 , R 2 , R 3 , and R 4 , are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.