| 1355979-31-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 1355979-31-5
• 化学式: C₂₁H₃₂NO₃*K
• 分子量: 385.588
• InChiKey: MNCZGSPAIIAXTJ-UNTBIKODSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.57
• 重原子数：
  26.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  72.72
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  tris(triphenylphosphine)ruthenium(II) chloride 、 以 丙酮 为溶剂， 生成 R(-)SALDiterBuleu Ru
  参考文献：
  名称：

  Synthesis, physico-chemical studies and solvent-dependent enantioselective epoxidation of 1,2-dihydronaphthalene catalysed by chiral Ruthenium(II) Schiff base complexes. I

  摘要：

  Ruthenium(II) chiral Schiff base complexes 1-10 and their precursor ligands derived from L-amino acids viz. L-leucine, L-histidine with salicylaldehyde, 3-tertiary-butyl-, 3,5-di-tertiary-butyl-, 3,5 dichloro- and 3,5-dinitrosalicylaldehyde are reported. The characterization of the ligands and complexes was accomplished by various appropriate physico-chemical studies, namely, microanalysis, IR-, UV/Vis-, H-1, P-31{H-1} NMR, CD spectroscopy, optical rotation, conductance measurement and cyclic voltammetry. The complexes thus synthesised were used as catalysts for enantioselective epoxidation of 1,2-dihydronaphthalene. The effect on enantioselectivity and chemical conversions to epoxide were studied in different solvents viz. acetonitrile, dichloromethane and fluorobenzene along with change of the substituents on ligands and different terminal oxidants. The less polar nature of solvent as well as the donating group attached on the catalysts favours enantioselectivity, while PhIO was the oxidant of choice. The enantiomeric excess of the resulting epoxide was evaluated by chiral cyclodex BDA capillary column. (C) 1999 Elsevier Science. B.V. All rights reserved.

  DOI：

  10.1016/s1381-1169(99)00226-5
• 作为产物：
  描述：

  D-亮氨酸 、 3,5-二叔丁基水杨醛 在 potassium hydroxide 作用下， 以 甲醇 为溶剂， 以83%的产率得到
  参考文献：
  名称：

  锌席夫碱配合物催化酮的高效，便捷的不对称氢化硅烷化

  摘要：

  制备了几种衍生自α-氨基酸的手性席夫碱配体，并测试了与所制备的手性席夫碱配体的锌配合物对酮的催化不对称氢化硅烷化作用，结果表明获得了优异的ee值，这是突出的例子锌络合物催化的酮的催化不对称氢化硅烷化反应的制备，存在容易获得和廉价的基于α-氨基酸的席夫碱配体。

  DOI：

  10.1016/j.tet.2011.12.054