1,1,2,2,3,3,4,4-octafluoro-7-aminooct-6-en-5-one | 72721-36-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1,2,2,3,3,4,4-octafluoro-7-aminooct-6-en-5-one
• 英文别名: (Z)-2-amino-5,5,6,6,7,7,8,8-octafluorooct-2-en-4-one
• CAS: 72721-36-9
• 化学式: C₈H₇F₈NO
• 分子量: 285.137
• InChiKey: QBIQPEYAUNGGNE-IHWYPQMZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  5,5,6,6,7,7,8,8-octafluoro-octane-2,4-dione 在 氨 作用下， 以 乙醚 为溶剂， 生成 1,1,2,2,3,3,4,4-octafluoro-7-aminooct-6-en-5-one
  参考文献：
  名称：

  Salt formation by reaction of fluorine-containing ?-diketones with amines

  摘要：

  DOI：

  10.1007/bf00995699

文献信息

• Interaction of fluoroalkyl-containing ?-diketones with amines
  作者：V. I. Filyakova、Y. G. Ratner、N. S. Karpenko、K. I. Pashkevich

  DOI：10.1007/bf01430731

  日期：1996.9

  The composition of products of the interaction of asymmetric fluoroalkyl-containing beta-diketones with amines was studied. Mixtures of regioisomeric beta-aminovinylketones and products of cleavage and secondary condensation are formed, depending on the temperature, the solvent, the nature of the fluorinated and nonfluorinated substituents in the beta-diketone, and the basicity of the amine. The major product is a beta-aminovinylketone in which the NH2 group is removed from the fluoroalkyl substituent. No beta-aminovinylimines, products of condensation involving two electrophilic centers, were observed.
• Karpenko; Filyakova; Pashkevich, Russian Journal of Organic Chemistry, 1997, vol. 33, # 12, p. 1724 - 1726
  作者：Karpenko、Filyakova、Pashkevich

  DOI：——

  日期：——
• Exchange reaction between fluorine-containing ?-diketones and ?-aminovinylketones
  作者：V. I. Filyakova、K. I. Pashkevich

  DOI：10.1007/bf00953748

  日期：1989.1
• Salt formation by reaction of fluorine-containing ?-diketones with amines
  作者：K. I. Pashkevich、V. I. Filyakova

  DOI：10.1007/bf00995699

  日期：1984.3