N-Glykolyl-D-glucosamin | 16426-37-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-Glykolyl-D-glucosamin
• 英文别名: 2-hydroxy-N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
• CAS: 16426-37-2
• 化学式: C₈H₁₅NO₇
• 分子量: 237.21
• InChiKey: ISMNOIMBJZMCCK-LRSZDJBLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.1
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  147
• 氢给体数：
  6
• 氢受体数：
  7

文献信息

• MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS
  申请人：Adamczyk Maciej

  公开号：US20120115244A1

  公开（公告）日：2012-05-10

  Methods of assaying for (i) a pterin by immunoassay employing a pterin as capture agent, (ii) neopterin by chemiluminescent microparticle immunoassay (CMIA) employing an anti-neopterin antibody (Ab) as capture agent, (iii) neopterin by an immunoassay (IA) employing an acridinium (Acr)-labeled anti-neopterin Ab as conjugate, and (iv) neopterin by an IA employing Acr-labeled neopterin as tracer; an Acr-labeled anti-neopterin Ab; a conjugate/complex comprising anti-neopterin Ab and a carrier scaffold; a conjugated pterin; a conjugate comprising an Acr-labeled pterin and a carrier scaffold; an immunogen comprising neopterin and a carrier protein; a conjugate comprising such an immunogen and an Acr compound; an immunogen comprising a carrier protein and a neopterin hapten; a conjugate comprising such an immunogen and an Acr compound; a kit for assaying a pterin comprising a pterin as a capture agent and instructions for IA; and a kit for assaying neopterin comprising an anti-neopterin Ab as a capture agent and instructions for CMIA, neopterin comprising an Acr-labeled anti-neopterin Ab as a conjugate and instructions for IA, or Acr-labeled neopterin as a tracer and instructions for IA.

  测定(i)一种黄素的免疫测定方法，采用一种黄素作为捕获试剂，(ii)一种新生黄素的化学发光微粒免疫测定(CMIA)方法，采用一种抗新生黄素抗体(Ab)作为捕获试剂，(iii)一种新生黄素的免疫测定(IA)方法，采用一种荧光素(Acr)标记的抗新生黄素抗体作为结合物，以及(iv)一种新生黄素的免疫测定方法，采用Acr标记的新生黄素作为追踪物；一种Acr标记的抗新生黄素抗体；一种包含抗新生黄素抗体和载体支架的结合物/复合物；一种共轭的黄素；一种包含Acr标记的黄素和载体支架的结合物；一种含有新生黄素和载体蛋白的免疫原；一种包含这种免疫原和Acr化合物的结合物；一种含有载体蛋白和新生黄素半抗原的免疫原；一种包含这种免疫原和Acr化合物的结合物；一种黄素测定试剂盒，包括一种黄素作为捕获试剂和IA的说明书；以及一种新生黄素测定试剂盒，包括一种抗新生黄素抗体作为捕获试剂和CMIA的说明书，或者包括一种Acr标记的抗新生黄素抗体作为结合物和IA的说明书，或者包括一种Acr标记的新生黄素作为追踪物和IA的说明书。
• Use of a N-acetylneuraminate lyase derived from the bacterium Aliivibrio salmonicida in the production of neuraminic acid and derivatives thereof
  申请人：Universitetet i Tromsø-Norges Arktiske Universitet

  公开号：US10378034B2

  公开（公告）日：2019-08-13

  The present invention provides to methods for the production of neuraminic acid or derivatives thereof under alkaline conditions and to the use of neuraminate lyases showing improved characteristics under alkaline conditions in the production of neuraminic acid or its derivatives. More particularly, the present invention employs inter alia a N-acetylneuraminate lyase which has been isolated from the psychrophilic bacterium Aliivibrio salmonicida LFI1238 and has shown to have improved characteristics under alkaline conditions.

  本发明提供了在碱性条件下生产神经氨酸或其衍生物的方法，以及使用在碱性条件下显示出改进特性的神经氨酸裂解酶来生产神经氨酸或其衍生物。更具体地说，本发明特别采用了一种N-乙酰神经氨酸裂解酶，该酶已从嗜精神细菌沙门氏菌（Aliivibrio salmonicida LFI1238）中分离出来，并已证明在碱性条件下具有更好的特性。
• Methods and kits for decreasing interferences from leukocytes in specific binding assays
  申请人：Yoshimura Toru

  公开号：US10641768B2

  公开（公告）日：2020-05-05

  The present disclosure describes methods and kits for reducing interferences in immunoassays performed on solid phase and on samples containing serum or plasma, by adding an effective amount of a polycationic derivative of dextran to the assay.

  本公开内容介绍了在固相和含有血清或血浆的样品上进行免疫测定时，通过在测定中添加有效量的右旋糖酐聚阳离子衍生物来减少干扰的方法和试剂盒。
• Delivery of peroxide-generating enzymes to the vaginal tract
  申请人：——

  公开号：US20040126369A1

  公开（公告）日：2004-07-01

  The present invention relates to methods and compositions for intravaginal administration of peroxide-generating enzymes and substrates for promoting the growth of Gram-positive bacilli, inhibiting Gram-negative bacilli, promoting an oxidizing environment, and/or treating or preventing disturbances of the vaginal bacterial flora accompanying the reduction of Gram-positive bacilli or the increase in pathogenic microbes, such as Gram-negative bacilli, resulting in vaginal infections.

  本发明涉及阴道内给药过氧化物生成酶和底物的方法和组合物，用于促进革兰氏阳性杆菌生长，抑制革兰氏阴性杆菌，促进氧化环境，和/或治疗或预防伴随革兰氏阳性杆菌减少或致病微生物（如革兰氏阴性杆菌）增加而导致阴道感染的阴道细菌菌群紊乱。
• DELIVERY OF PEROXIDE-GENERATING ENZYMES TO THE VAGINAL TRACT
  申请人：KIMBERLY-CLARK WORLDWIDE, INC.

  公开号：EP1578317A2

  公开（公告）日：2005-09-28