phenyl 2-azido-2-deoxy-4-O-p-methoxybenzyl-1-thio-3-O-triisopropylsilyl-α-D-glucopyranose | 1401695-32-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: phenyl 2-azido-2-deoxy-4-O-p-methoxybenzyl-1-thio-3-O-triisopropylsilyl-α-D-glucopyranose
• CAS: 1401695-32-6
• 化学式: C₂₉H₄₃N₃O₅SSi
• 分子量: 573.829
• InChiKey: NJLJJPBJHJBDBW-HWVUQVAQSA-N

反应信息

• 作为产物：
  描述：

  在 硼烷四氢呋喃络合物 、 三氟甲磺酸二丁硼 作用下， 生成 phenyl 2-azido-2-deoxy-4-O-p-methoxybenzyl-1-thio-3-O-triisopropylsilyl-β-D-glucopyranose 、 phenyl 2-azido-2-deoxy-4-O-p-methoxybenzyl-1-thio-3-O-triisopropylsilyl-α-D-glucopyranose
  参考文献：
  名称：

  Synthesis of a Benzomacrolactone-Based Somatostatin Mimetic

  摘要：

  The benzomacrolactone is a framework found in numerous natural products. The synthesis of an orthogonally functionalized benzomacrolactone from D-glucosamine and a salicylic acid derivative is described. This macrolactone was used for the synthesis of a somatostatin mimetic that has submicromolar affinity for the human somatostatin receptor 4 (hSSTR4).

  DOI：

  10.1021/ol202528k