N-[(15-crown-5)-2-yl]-N,N-bis(2-diethoxyphosphorylethyl)amine | 890935-93-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: N-[(15-crown-5)-2-yl]-N,N-bis(2-diethoxyphosphorylethyl)amine
• 英文别名: 2-diethoxyphosphoryl-N-(2-diethoxyphosphorylethyl)-N-(1,4,7,10,13-pentaoxacyclopentadec-2-ylmethyl)ethanamine
• CAS: 890935-93-0
• 化学式: C₂₃H₄₉NO₁₁P₂
• 分子量: 577.59
• InChiKey: RWSKWJXJEWXJIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  37
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  120
• 氢给体数：
  0
• 氢受体数：
  12

文献信息

• Novel cationic metal complex radiopharmaceuticals
  申请人：Liu Shuang

  公开号：US20080124273A1

  公开（公告）日：2008-05-29

  This invention relates to novel cationic crown-ether containing metal complexes, methods of preparing the cationic crown-ether containing metal complexes, and radiopharmaceutical compositions comprising the cationic crown-ether containing metal complexes. This invention relates particularly to cationic crown-ether containing 99m Tc complex radiopharmaceuticals for diagnosis of cardiovascular disorders and cancer. This invention further relates to cationic crown-ether containing 186/188 Re complex radiopharmaceuticals for radiotherapy of cardiovascular disorders and cancer.
• [EN] NOVEL CATIONIC METAL COMPLEX RADIOPHARMACEUTICALS<br/>[FR] RADIOPHARMACEUTIQUES A COMPLEXES METALLIQUES CATIONIQUES
  申请人：PURDUE RESEARCH FOUNDATION

  公开号：WO2006080993A1

  公开（公告）日：2006-08-03

  [EN] This invention relates to novel cationic crown-ether containing metal complexes, methods of preparing the cationic crown-ether containing metal complexes, and radiopharmaceutical compositions comprising the cationic crown-ether containing metal complexes. This invention relates to cationic crown-ether containing ^99m Tc complex radiopharmaceuticals for diagnosis of cardiovascular disorders and cancer. This invention further relates to cationic crown-ether containing ^186/188 Re complex radiopharmaceuticals for radiotherapy of cardiovascular disorders and cancer.
  [FR] L'invention concerne de nouveaux complexes métalliques contenant un éther couronne cationique, des procédés pour préparer ces complexes métalliques contenant un éther couronne cationique et des compositions radiopharmaceutiques comportant des complexes métalliques contenant un éther couronne cationique. La présente invention porte également sur des radiopharmaceutiques complexes ^99m Tc contenant un éther couronne cationique pour le diagnostic de troubles cardio-vasculaires et du cancer, ainsi que sur des radiopharmaceutiques complexes ^186/188 Re contenant un éther couronne cationique pour la radiothérapie de troubles cardio-vasculaires et du cancer.