nitrophenyl-α-L-rhamnopyranoside | 18918-28-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: nitrophenyl-α-L-rhamnopyranoside
• 英文别名: (2S,3R,4R,5R,6S)-2-methyl-6-(2-nitrophenoxy)oxane-3,4,5-triol
• CAS: 18918-28-0
• 化学式: C₁₂H₁₅NO₇
• 分子量: 285.254
• InChiKey: SWRPIVXPHLYETN-UOAXWKJLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  125
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• LECTIN-DIRECTED PRODRUG DELIVERY SYSTEM
  申请人：ISIS INNOVATION LIMITED

  公开号：EP1372734A1

  公开（公告）日：2004-01-02
• [EN] LECTIN-DIRECTED PRODRUG DELIVERY SYSTEM<br/>[FR] SYSTEME D'ADMINISTRATION DE PROMEDICAMENT ORIENTE LECTINE
  申请人：ISIS INNOVATION

  公开号：WO2002080980A1

  公开（公告）日：2002-10-17

  The invention provides a kit for lectin-directed prodrug delivery comprising a prodrug and a lectin-directed glycoconjugate, wherein the glycoconjugate is adapted to cleave the prodrug and thereby release the drug. The glycoconjugate generally comprises an enzyme conjugated to a carbohydrate moiety which binds to a lectin. The invention also provides novel glycoconjugates and novel methods of synthesizing prodrugs.