S-(4-hydroxybutyl) 2,2-dimethylpropanethioate | 202478-83-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: S-(4-hydroxybutyl) 2,2-dimethylpropanethioate
• CAS: 202478-83-9
• 化学式: C₉H₁₈O₂S
• 分子量: 190.307
• InChiKey: XILLQZAOWCGBNJ-UHFFFAOYSA-N

物化性质

• 沸点：
  270.5±23.0 °C(Predicted)
• 密度：
  1.024±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  62.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  S-(4-hydroxybutyl) 2,2-dimethylpropanethioate 在 四氮唑 、 叔丁基过氧化氢 、 三乙胺 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 生成 2,2-Dimethyl-thiopropionic acid S-(4-{[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-[4-(2,2-dimethyl-propionylsulfanyl)-butoxy]-phosphoryloxy}-butyl) ester
  参考文献：
  名称：

  Effect of the Thioalkyl Chain Variation in the Efficiency of Sate Pronucleotides

  摘要：

  The synthesis and the anti-HIV activity of two mononucleoside phosphotriester derivatives of 3'-azido-2',3"-dideoxythymidine (AZT) and 2',3'-dideoxyadenosine (ddA) incorporating a new kind of phosphate protecting group, namely S-pivaloyl-4-thiobutyl (tBuSATB), are reported.

  DOI：

  10.1080/07328319808004707
• 作为产物：
  描述：

  4-碘-1-丁醇 、 硫代特戊酸 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 甲苯 为溶剂， 反应 4.0h， 以88%的产率得到S-(4-hydroxybutyl) 2,2-dimethylpropanethioate
  参考文献：
  名称：

  Egron, D.; Perigaud, C.; Gosselin, G., Bulletin des Societes Chimiques Belges, 1997, vol. 106, # 7-8, p. 461 - 466

  摘要：

  DOI：

文献信息

• Egron, D.; Perigaud, C.; Gosselin, G., Bulletin des Societes Chimiques Belges, 1997, vol. 106, # 7-8, p. 461 - 466
  作者：Egron, D.、Perigaud, C.、Gosselin, G.、Aubertin, A.-M.、Imbach, J. L.

  DOI：——

  日期：——
• BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIUM AND MAGNETIC RECORDING MEDIUM
  申请人：YOSHIZAWA Masataka

  公开号：US20110244270A1

  公开（公告）日：2011-10-06

  An aspect of the present invention relates to a binder composition for a magnetic recording medium, which comprises a vinyl copolymer comprising a structural unit denoted by general formula [1]: wherein, in general formula [1], R 1 denotes a hydrogen atom, a halogen atom, or a methyl group, L 1 denotes a single bond or a divalent linking group, and Y an alicyclic group; a structural unit denoted by general formula [2]: wherein, in general formula [2], R 2 denotes a hydrogen atom, a halogen atom, or a methyl group, L 2 denotes a single bond or a divalent linking group, and Z denotes a hydrocarbon group with a carbon number ranging from 8 to 50; and a structural unit denoted by general formula [3]: wherein, in general formula [3], R 3 denotes a hydrogen atom, a halogen atom, or a methyl group, and L 3 denotes a single bond or a divalent linking group.
• Effect of the Thioalkyl Chain Variation in the Efficiency of Sate Pronucleotides
  作者：D. Egron、C. Perigaud、A.-M. Aubertin、J.-L. Imbach、G. Gosselin

  DOI：10.1080/07328319808004707

  日期：1998.9

  The synthesis and the anti-HIV activity of two mononucleoside phosphotriester derivatives of 3'-azido-2',3"-dideoxythymidine (AZT) and 2',3'-dideoxyadenosine (ddA) incorporating a new kind of phosphate protecting group, namely S-pivaloyl-4-thiobutyl (tBuSATB), are reported.