Dimethyl 2-(2-oxohexyl)pentanedioate | 476363-09-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: Dimethyl 2-(2-oxohexyl)pentanedioate
• 英文别名: dimethyl 2-(2-oxohexyl)pentanedioate
• CAS: 476363-09-4
• 化学式: C₁₃H₂₂O₅
• 分子量: 258.315
• InChiKey: PAEGQAOYUFYLAX-UHFFFAOYSA-N

物化性质

• 沸点：
  345.1±27.0 °C(Predicted)
• 密度：
  1.043±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  69.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  正戊醛 、 丙烯酸甲酯（MA） 在 N-羟基邻苯二甲酰亚胺 、 过氧化苯甲酰 作用下， 以 甲苯 为溶剂， 以80%的产率得到methyl 4-oxooctanoate
  参考文献：
  名称：

  Addition of aldehydes and their equivalents to electron-deficient alkenes using N-hydroxyphthalimide (NHPI) as a polarity-reversal catalyst

  摘要：

  Radical addition of aldehydes and masked aldehydes like 1,3-dioxolanes to electron-deficient alkenes was achieved by the use of catalytic amounts of BPO and N-hydroxyphthalimide (NHPI) as a polarity-reversal catalyst under mild conditions. Three-component radical coupling of 1,3-dioxolanes, maleates, and alkenes was performed in the presence of BPO and NHPI under similar conditions. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)01375-3

文献信息

• Addition of aldehydes and their equivalents to electron-deficient alkenes using N-hydroxyphthalimide (NHPI) as a polarity-reversal catalyst
  作者：Shinya Tsujimoto、Satoshi Sakaguchi、Yasutaka Ishii

  DOI：10.1016/s0040-4039(03)01375-3

  日期：2003.7

  Radical addition of aldehydes and masked aldehydes like 1,3-dioxolanes to electron-deficient alkenes was achieved by the use of catalytic amounts of BPO and N-hydroxyphthalimide (NHPI) as a polarity-reversal catalyst under mild conditions. Three-component radical coupling of 1,3-dioxolanes, maleates, and alkenes was performed in the presence of BPO and NHPI under similar conditions. (C) 2003 Elsevier Ltd. All rights reserved.