9-甲基癸-7-烯酸 | 61229-05-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 9-甲基癸-7-烯酸
• 英文名称: cis-9-methyl-7-decenoic acid
• 英文别名: (Z)-9-methyldec-7-enoic acid
• CAS: 61229-05-8；62356-05-2
• 化学式: C₁₁H₂₀O₂
• 分子量: 184.279
• InChiKey: MAXWNMPBFJYJBB-VURMDHGXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  9-甲基癸-7-烯酸 在 氯化亚砜 作用下， 生成 9-methyldec-7-enoyl chloride
  参考文献：
  名称：

  Capsaicinoids: their separation, synthesis, and mutagenicity

  摘要：

  DOI：

  10.1021/jo00240a024
• 作为产物：
  描述：

  7-羟基庚酸甲酯 在 氢氧化钾 、 potassium tert-butylate 、 sodium acetate 、 pyridinium chlorochromate 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 23.58h， 生成 9-甲基癸-7-烯酸
  参考文献：
  名称：

  Capsaicinoids: their separation, synthesis, and mutagenicity

  摘要：

  DOI：

  10.1021/jo00240a024

文献信息

• LONG CHAIN FATTY ACID FORMULATIONS AND THEIR USE IN INHIBITING SALMONELLA INFECTION
  申请人：CORNELL UNIVERSITY

  公开号：US20200330420A1

  公开（公告）日：2020-10-22

  A method for inhibiting or preventing Salmonella invasion of the intestinal epithelium in a subject, the method comprising enterally administering to the subject a pharmaceutically effective amount of a fatty acid dissolved or suspended in a pharmaceutically acceptable carrier, wherein the fatty acid contains 10 to 30 carbon atoms, wherein the fatty acid is more particularly an unsaturated fatty acid containing 1-4 carbon-carbon double bonds and/or 1 or 2 carbon-carbon triple bonds, or the fatty acid is more particularly a cis-unsaturated fatty acid, or the fatty acid is more particularly a cis-2-unsaturated fatty acid having the formula: wherein n is an integer of 6-26, and the fatty acid optionally includes a second carbon-carbon double bond resulting from removal of two hydrogen atoms on adjacent carbon atoms.
• [EN] COMPOSITIONS AND METHODS FOR INHIBITING VIBRIO INFECTION<br/>[FR] COMPOSITIONS ET MÉTHODES D'INHIBITION D'UNE INFECTION PAR VIBRIO
  申请人：UNIV CORNELL

  公开号：WO2021202632A2

  公开（公告）日：2021-10-07

  Disclosed herein is a method for inhibiting or preventing Vibrio cholera toxin production in a subject, the method comprising enterally administering to the subject a pharmaceutically effective amount of a fatty acid dissolved or suspended in a pharmaceutically acceptable carrier, wherein the fatty acid contains 10 to 30 carbon atoms, such as an unsaturated fatty acid such as a cis-2-unsaturated fatty acid, such as a fatty acid having the formula (1) wherein n is an integer of 6-26, and the fatty acid optionally includes a second carbon-carbon double bond resulting from removal of two hydrogen atoms on adjacent carbon atoms. Also disclosed herein is a method for treating or preventing a Vibrio infection comprising administering to a subject in need of treatment an effective amount of a genetically engineered bacterium, wherein the genetically engineered bacterium comprises an exogenous nucleic acid encoding an enzyme that produces a diffusible signal factor (DSF) by introducing a cis-2 double bond to a fatty acid.