N-((3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-benzamide | 32442-81-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-((3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-benzamide
• 英文别名: N-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]benzamide
• CAS: 32442-81-2
• 化学式: C₁₃H₁₇NO₆
• 分子量: 283.281
• InChiKey: SPYSOSUFGSNSMY-TWEVDUBQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  119
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• [EN] NOVEL OLIGOSACCHARIDE GLYCOSIDES HAVING MAMMALIAN IMMUNOSUPPRESSIVE AND TOLEROGENIC PROPERTIES<br/>[FR] NOUVEAUX GLYCOSIDES OLIGOSACCHARIDIQUES AYANT DES PROPRIETES IMMUNOSUPPRESSIVES ET TOLEROGENES CHEZ LES MAMMIFERES
  申请人：GLYCOMED, INC.

  公开号：WO1997018222A2

  公开（公告）日：1997-05-22

  (EN) Disclosed are novel oligosaccharide glycosides having mammalian immunosuppressive and tolerogenic properties, pharmaceutical compositions containing such oligosaccharide glycosides and methods of using such oligosaccharide glycosides to modulate cell-mediated immune responses in a mammal.(FR) L'invention concerne de nouveaux glycosides oligosaccharidiques possédant des propriétés immunosuppressives et tolérogènes chez les mammifères, des compositions pharmaceutiques les contenant et des procédés d'utilisation de ces glycosides pour moduler les réponses immunes induites par les cellules chez un mammifère.
• [EN] MONOSACCHARIDE DERIVATIVES<br/>[FR] DERIVES DE MONOSACCHARIDES
  申请人：UNIV DUBLIN

  公开号：WO2003018598A2

  公开（公告）日：2003-03-06

  Monosaccharide (pyranoside) conjugates of the formula have been found to be useful as enhancers and/or inhibitors of heparin binding to FGF. The compounds have the potential to be useful in regenerative medicine or for treatment of pathological disease associated with FGF activity or as glycoprocessing inhibitors. In particular the compounds are potential modulators of fibroblast growth factors (FGFs) and fibronectin, as mitogenic agents and as inhibitors of endothelial cell survival.